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Case Reports
. 2021 Mar 1;14(1):239-243.
doi: 10.1159/000512067. eCollection 2021 Jan-Apr.

Clear Cell Chondrosarcoma with Rib Cage Metastasis: Case Report

Rui Caetano de Oliveira  1   2 , John Reith  3 , José Casanova  2   4   5
Affiliations
Case Reports

Clear Cell Chondrosarcoma with Rib Cage Metastasis: Case Report

Rui Caetano de Oliveira et al. Case Rep Oncol. .

Abstract

Clear cell chondrosarcoma is a rare histological subtype of chondrosarcoma, usually with a relatively non-aggressive clinical course. However, infrequently they may relapse and metastasize. We describe a case of a male patient, 53 years old, with rib cage metastases of a clear cell chondrosarcoma 11 years after the first surgical intervention, and review the literature.

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Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Fig. 1
Fig. 1
Gross inspection of periacetabular pelvic resection: there is a whitish lesion with hemorrhagic and necrotic areas, surrounding bone and with soft tissue component. Negative surgical margins were achieved resorting to wide resection.
Fig. 2
Fig. 2
a Tumour revealed a diffuse cell proliferation surrounding trabeculae of woven bone (H&E, ×40). b The tumour cells exhibited clear cell cytoplasm and moderate nuclear atypia (H&E, ×200).
Fig. 3
Fig. 3
a Chest X-ray showed a lytic lesion of the rib cage (blue arrow). b Computed tomography (CT scan) confirmed the lytic lesion, on the 7th right rib, centred in the bone.
Fig. 4
Fig. 4
a Histological evaluation revealed a diffuse cellular proliferation (H&E, ×20). b The cells had clear cell cytoplasm with well-defined boundaries and visible nucleoli, with areas of mature cartilage (H&E, ×200).
See this image and copyright information in PMC

References

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