Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Mar 11:12:573237.
doi: 10.3389/fneur.2021.573237. eCollection 2021.

Hyperventilation in Severe Traumatic Brain Injury Has Something Changed in the Last Decade or Uncertainty Continues? A Brief Review

Daniel Agustín Godoy  1   2 , Rafael Badenes  3   4   5 , Chiara Robba  6   7 , Francisco Murillo Cabezas  8
Affiliations

Hyperventilation in Severe Traumatic Brain Injury Has Something Changed in the Last Decade or Uncertainty Continues? A Brief Review

Daniel Agustín Godoy et al. Front Neurol. .
No abstract available

Keywords: cerebral hypoxia; cerebral ischemia; hyperventilation; hypocapnia; intracranial hypertension; intracranial pressure; severe traumatic brain injury.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Graphical Abstract
Graphical Abstract
Diagram about the mechanisms in which hyperventilation affects the brain pathophysiology.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Godoy DA, Seifi A, Garza D, Lubillo-Montenegro S, Murillo-Cabezas F. Hyperventilation therapy for control of posttraumatic intracranial hypertension. Front Neurol. (2017) 8: 250. 10.3389/fneur.2017.00250 - DOI - PMC - PubMed
    1. Carney N, Totten AM, O'Reilly C, Ullman JS, Hawryluk GW, Bell MJ, et al. . Guidelines for the management of severe traumatic brain injury, Fourth Edition. Neurosurgery. (2017) 80:6–15. 10.1227/NEU.0000000000001432 - DOI - PubMed
    1. Harper AM, Glass HI. Effect of alterations in the arterial carbon dioxide tension on the blood flow through the cerebral cortex at normal and low arterial blood pressures. J Neurol Neurosurg Psychiatr. (1965) 28: 449–52. 10.1136/jnnp.28.5.449 - DOI - PMC - PubMed
    1. Brian JE. Carbon dioxide and the cerebral circulation. Anesthesiology. (1998) 88:365–86. 10.1097/00000542-199805000-00029 - DOI - PubMed
    1. Cold GE. Cerebral blood flow in acute head injury. The regulation of cerebral blood flow and metabolism during the acute phase of head injury, and itssignificance for therapy. Acta Neurochir Suppl. (1990) 49:1– 64. 10.1007/978-3-7091-9101-9_1 - DOI - PubMed