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Review
. 2021 Mar 10:11:607150.
doi: 10.3389/fonc.2021.607150. eCollection 2021.

Circulating Tumor Cells for Glioma

Huikai Zhang  1 , Fanen Yuan  1 , Yangzhi Qi  1 , Baohui Liu  1 , Qianxue Chen  1
Affiliations
Review

Circulating Tumor Cells for Glioma

Huikai Zhang et al. Front Oncol. .

Abstract

Liquid biopsy has entered clinical applications for several cancers, including metastatic breast, prostate, and colorectal cancer for CTC enumeration and NSCLC for EGFR mutations in ctDNA, and has improved the individualized treatment of many cancers, but relatively little progress has been made in validating circulating biomarkers for brain malignancies. So far, data on circulating tumor cells about glioma are limited, the application of circulating tumor cells as biomarker for glioma patients has only just begun. This article reviews the research status and application prospects of circulating tumor cells in gliomas. Several detection methods and research results of circulating tumor cells about clinical research in gliomas are briefly discussed. The wide application prospect of circulating tumor cells in glioma deserves further exploration, and the research on more sensitive and convenient detection methods is necessary.

Keywords: biomarker; blood; circulating tumor cells; glioma; liquid biopsy.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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