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. 2021 Feb 16;8(3):ofab074.
doi: 10.1093/ofid/ofab074. eCollection 2021 Mar.

Cutaneous Findings in SARS-CoV-2-Associated Multisystem Inflammatory Disease in Children

Allison M Blatz  1 , Michelle Oboite  2   3 , Kathleen Chiotos  1   4   3 , Leslie Castelo-Soccio  2   3 , Audrey R Odom John  1   3 ; Children’s Hospital of Philadelphia MIS-C Research Collaborative
Collaborators, Affiliations

Cutaneous Findings in SARS-CoV-2-Associated Multisystem Inflammatory Disease in Children

Allison M Blatz et al. Open Forum Infect Dis. .

Abstract

Rash is a common feature of multisystem inflammatory syndrome in children (MIS-C), a postinfectious hyperinflammatory disease associated with prior severe acute respiratory syndrome coronavirus 2 infection. Because the differential diagnosis of fever and rash in children is broad, understanding clinical characteristics of MIS-C may assist with diagnosis. Here we describe the cutaneous findings observed in a series of children with MIS-C-associated rash.

Keywords: MIS-C; SARS-CoV-2; pediatric infectious diseases; rash.

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Figures

Figure 1.
Figure 1.
Characteristic cutaneous findings in pediatric multisystem inflammatory syndrome in children. Arrows indicate regions of erythema.
See this image and copyright information in PMC

References

    1. Feldstein LR, Rose EB, Horwitz SM, et al. . Multisystem inflammatory syndrome in U.S. children and adolescents. N Engl J Med. In press. - PMC - PubMed
    1. Toubiana J, Poirault C, Corsia A, et al. . Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic in Paris, France: prospective observational study. BMJ 2020; 369:m2094. - PMC - PubMed
    1. Verdoni L, Mazza A, Gervasoni A, et al. . An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study. Lancet 2020; 395:1771–8. - PMC - PubMed
    1. Centers for Disease Control and Prevention. Multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease 2019 (COVID-19).2020. Available at: https://emergency.cdc.gov/han/2020/han00432.asp. Accessed 30 July 2020.
    1. Chiotos K, Bassiri H, Behrens EM, et al. . Multisystem inflammatory syndrome in children during the coronavirus 2019 pandemic: a case series. J Pediatric Infect Dis Soc. In press. - PMC - PubMed