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Multicenter Study
. 2021 Mar 1;4(3):e213287.
doi: 10.1001/jamanetworkopen.2021.3287.

Assessment of Diagnosis and Triage in Validated Case Vignettes Among Nonphysicians Before and After Internet Search

Affiliations
Multicenter Study

Assessment of Diagnosis and Triage in Validated Case Vignettes Among Nonphysicians Before and After Internet Search

David M Levine et al. JAMA Netw Open. .

Abstract

Importance: When confronted with new medical symptoms, many people turn to the internet to understand why they are ill as well as whether and where they should get care. Such searches may be harmful because they may facilitate misdiagnosis and inappropriate triage.

Objective: To empirically measure the association of an internet search for health information with diagnosis, triage, and anxiety by laypeople.

Design, setting, and participants: This survey study used a nationally representative sample of US adults who were recruited through an online platform between April 1, 2019, and April 15, 2019. A total of 48 validated case vignettes of both common (eg, viral illness) and severe (eg, heart attack) conditions were used. Participants were asked to relay their diagnosis, triage, and anxiety regarding 1 of these cases before and after searching the internet for health information.

Exposures: Short, validated case vignettes written at or below the sixth-grade reading level randomly assigned to participants.

Main outcomes and measures: Correct diagnosis, correct triage, and flipping (changing) or anchoring (not changing) diagnosis and triage decisions were the main outcomes. Multivariable modeling was performed to identify patient factors associated with correct triage and diagnosis.

Results: Of the 5000 participants, 2549 were female (51.0%), 3819 were White (76.4%), and the mean (SD) age was 45.0 (16.9) years. Mean internet search time was 12.1 (95% CI, 10.7-13.5) minutes per case. No difference in triage accuracy was found before and after search (74.5% vs 74.1%; difference, -0.4 [95% CI, -1.4 to 0.6]; P = .06), but improved diagnostic accuracy was found (49.8% vs 54.0%; difference, 4.2% [95% CI, 3.1%-5.3%]; P < .001). Most participants (4254 [85.1%]) were anchored on their diagnosis. Of the 14.9% of participants (n = 746) who flipped their diagnosis, 9.6% (n = 478) flipped from incorrect to correct and 5.4% (n = 268) flipped from correct to incorrect. The following groups had an increased rate of correct diagnosis: adults 40 years or older (eg, 40-49 years: 5.1 [95% CI, 0.8-9.4] percentage points better than those aged <30 years; P = .02), women (9.4 [95% CI, 6.8-12.0] percentage points better than men; P < .001), and those with perceived poor health status (16.3 [95% CI, 6.9-25.6] percentage points better than those with excellent status; P = .001) and with more than 2 chronic diseases (6.8 [95% CI, 1.5-12.1] percentage points better than those with 0 conditions; P = .01).

Conclusions and relevance: This study found that an internet search for health information was associated with small increases in diagnostic accuracy but not with triage accuracy.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Levine reported receiving grants from Biofourmis and IBM for PI-initiated studies outside the submitted work. No other disclosures were reported.

Figures

Figure 1.
Figure 1.. Diagnosis, Triage, and Anxiety Before and After an Internet Search, by Severity of Case
Error bars represent 95% CI. For panels A and B, the y-axis does not begin at 0.
Figure 2.
Figure 2.. Diagnostic Accuracy Before and After Internet Search, by Severity of Case
Figure 3.
Figure 3.. Anchoring or Flipping on Original Diagnosis and Triage
The intersection of blue and orange color blocks represents the percentage of patients who flipped their original diagnosis (A) or triage (B).

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