The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

Matthew J Page¹, Joanne E McKenzie², Patrick M Bossuyt³, Isabelle Boutron⁴, Tammy C Hoffmann⁵, Cynthia D Mulrow⁶, Larissa Shamseer⁷, Jennifer M Tetzlaff⁸, Elie A Akl⁹, Sue E Brennan², Roger Chou¹⁰, Julie Glanville¹¹, Jeremy M Grimshaw¹², Asbjørn Hróbjartsson¹³, Manoj M Lalu¹⁴, Tianjing Li¹⁵, Elizabeth W Loder¹⁶, Evan Mayo-Wilson¹⁷, Steve McDonald², Luke A McGuinness¹⁸, Lesley A Stewart¹⁹, James Thomas²⁰, Andrea C Tricco²¹, Vivian A Welch²², Penny Whiting¹⁸, David Moher²³

Affiliations

¹ School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia. matthew.page@monash.edu.
² School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
³ Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, Netherlands.
⁴ Université de Paris, Centre of Epidemiology and Statistics (CRESS), Inserm, F 75004, Paris, France.
⁵ Institute for Evidence-Based Healthcare, Faculty of Health Sciences and Medicine, Bond University, Gold Coast, Australia.
⁶ Annals of Internal Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
⁷ Knowledge Translation Program, Li Ka Shing Knowledge Institute, Toronto, Canada; School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
⁸ Evidence Partners, Ottawa, Canada.
⁹ Clinical Research Institute, American University of Beirut, Beirut, Lebanon; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
¹⁰ Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR, USA.
¹¹ York Health Economics Consortium (YHEC Ltd), University of York, York, UK.
¹² Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada; Department of Medicine, University of Ottawa, Ottawa, Canada.
¹³ Centre for Evidence-Based Medicine Odense (CEBMO) and Cochrane Denmark, Department of Clinical Research, University of Southern Denmark, JB Winsløwsvej 9b, 3rd Floor, 5000 Odense, Denmark; Open Patient data Exploratory Network (OPEN), Odense University Hospital, Odense, Denmark.
¹⁴ Department of Anesthesiology and Pain Medicine, The Ottawa Hospital, Ottawa, Canada; Clinical Epidemiology Program, Blueprint Translational Research Group, Ottawa Hospital Research Institute, Ottawa, Canada; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Canada.
¹⁵ Department of Ophthalmology, School of Medicine, University of Colorado Denver, Denver, Colorado, United States; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
¹⁶ Division of Headache, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; Head of Research, The BMJ, London, UK.
¹⁷ Department of Epidemiology and Biostatistics, Indiana University School of Public Health-Bloomington, Bloomington, Indiana, USA.
¹⁸ Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
¹⁹ Centre for Reviews and Dissemination, University of York, York, UK.
²⁰ EPPI-Centre, UCL Social Research Institute, University College London, London, UK.
²¹ Li Ka Shing Knowledge Institute of St. Michael's Hospital, Unity Health Toronto, Toronto, Canada; Epidemiology Division of the Dalla Lana School of Public Health and the Institute of Health Management, Policy, and Evaluation, University of Toronto, Toronto, Canada; Queen's Collaboration for Health Care Quality Joanna Briggs Institute Centre of Excellence, Queen's University, Kingston, Canada.
²² Methods Centre, Bruyère Research Institute, Ottawa, Ontario, Canada; School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
²³ Centre for Journalology, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada; School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada.

PMID: 33781348
PMCID: PMC8008539
DOI: 10.1186/s13643-021-01626-4

The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

Matthew J Page et al. Syst Rev. 2021.

. 2021 Mar 29;10(1):89.

doi: 10.1186/s13643-021-01626-4.

Authors

Affiliations

¹ School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia. matthew.page@monash.edu.
² School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
³ Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, Netherlands.
⁴ Université de Paris, Centre of Epidemiology and Statistics (CRESS), Inserm, F 75004, Paris, France.
⁵ Institute for Evidence-Based Healthcare, Faculty of Health Sciences and Medicine, Bond University, Gold Coast, Australia.
⁶ Annals of Internal Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
⁷ Knowledge Translation Program, Li Ka Shing Knowledge Institute, Toronto, Canada; School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
⁸ Evidence Partners, Ottawa, Canada.
⁹ Clinical Research Institute, American University of Beirut, Beirut, Lebanon; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
¹⁰ Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR, USA.
¹¹ York Health Economics Consortium (YHEC Ltd), University of York, York, UK.
¹² Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada; Department of Medicine, University of Ottawa, Ottawa, Canada.
¹³ Centre for Evidence-Based Medicine Odense (CEBMO) and Cochrane Denmark, Department of Clinical Research, University of Southern Denmark, JB Winsløwsvej 9b, 3rd Floor, 5000 Odense, Denmark; Open Patient data Exploratory Network (OPEN), Odense University Hospital, Odense, Denmark.
¹⁴ Department of Anesthesiology and Pain Medicine, The Ottawa Hospital, Ottawa, Canada; Clinical Epidemiology Program, Blueprint Translational Research Group, Ottawa Hospital Research Institute, Ottawa, Canada; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Canada.
¹⁵ Department of Ophthalmology, School of Medicine, University of Colorado Denver, Denver, Colorado, United States; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
¹⁶ Division of Headache, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; Head of Research, The BMJ, London, UK.
¹⁷ Department of Epidemiology and Biostatistics, Indiana University School of Public Health-Bloomington, Bloomington, Indiana, USA.
¹⁸ Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
¹⁹ Centre for Reviews and Dissemination, University of York, York, UK.
²⁰ EPPI-Centre, UCL Social Research Institute, University College London, London, UK.
²¹ Li Ka Shing Knowledge Institute of St. Michael's Hospital, Unity Health Toronto, Toronto, Canada; Epidemiology Division of the Dalla Lana School of Public Health and the Institute of Health Management, Policy, and Evaluation, University of Toronto, Toronto, Canada; Queen's Collaboration for Health Care Quality Joanna Briggs Institute Centre of Excellence, Queen's University, Kingston, Canada.
²² Methods Centre, Bruyère Research Institute, Ottawa, Ontario, Canada; School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
²³ Centre for Journalology, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada; School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada.

PMID: 33781348
PMCID: PMC8008539
DOI: 10.1186/s13643-021-01626-4

No abstract available

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Conflict of interest statement

All authors have completed the ICMJE uniform disclosure form at http://www.icmje.org/conflicts-of-interest/ and declare: EL is head of research for the BMJ; MJP is an editorial board member for PLOS Medicine; ACT is an associate editor and MJP, TL, EMW, and DM are editorial board members for the Journal of Clinical Epidemiology; DM and LAS were editors in chief, LS, JMT, and ACT are associate editors, and JG is an editorial board member for Systematic Reviews. None of these authors were involved in the peer review process or decision to publish. TCH has received personal fees from Elsevier outside the submitted work. EMW has received personal fees from the American Journal for Public Health, for which he is the editor for systematic reviews. VW is editor in chief of the Campbell Collaboration, which produces systematic reviews, and co-convenor of the Campbell and Cochrane equity methods group. DM is chair of the EQUATOR Network, IB is adjunct director of the French EQUATOR Centre and TCH is co-director of the Australasian EQUATOR Centre, which advocates for the use of reporting guidelines to improve the quality of reporting in research articles. JMT received salary from Evidence Partners, creator of DistillerSR software for systematic reviews; Evidence Partners was not involved in the design or outcomes of the statement, and the views expressed solely represent those of the author.

Figures

**Fig. 1**
PRISMA 2020 flow diagram template for systematic reviews. The new design is adapted from flow diagrams proposed by Boers [55], Mayo-Wilson et al. [56] and Stovold et al. [57] The boxes in grey should only be completed if applicable; otherwise they should be removed from the flow diagram. Note that a “report” could be a journal article, preprint, conference abstract, study register entry, clinical study report, dissertation, unpublished manuscript, government report or any other document providing relevant information

See this image and copyright information in PMC

References

1. Gurevitch J, Koricheva J, Nakagawa S, Stewart G. Meta-analysis and the science of research synthesis. Nature. 2018;555:175–182. doi: 10.1038/nature25753. - DOI - PubMed
1. Gough D, Thomas J, Oliver S. Clarifying differences between reviews within evidence ecosystems. Syst Rev. 2019;8:170. doi: 10.1186/s13643-019-1089-2. - DOI - PMC - PubMed
1. Moher D. Reporting guidelines: doing better for readers. BMC Med. 2018;16:233. doi: 10.1186/s12916-018-1226-0. - DOI - PMC - PubMed
1. Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med. 2009;151:264–269. doi: 10.7326/0003-4819-151-4-200908180-00135. - DOI - PubMed
1. Moher D, Liberati A, Tetzlaff J, Altman DG. PRISMA Group Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ. 2009;339:b2535. doi: 10.1136/bmj.b2535. - DOI - PMC - PubMed

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The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

Affiliations

The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

Authors

Affiliations

Conflict of interest statement

Figures

References

Publication types

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources

Other Literature Sources