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Comment
. 2021 Apr;53(4):429-430.
doi: 10.1038/s41588-021-00839-6.

Ultraconservation of enhancers is not ultranecessary

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Free article
Comment

Ultraconservation of enhancers is not ultranecessary

Maureen Pittman et al. Nat Genet. 2021 Apr.
Free article
No abstract available

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Comment on

  • Ultraconserved enhancer function does not require perfect sequence conservation.
    Snetkova V, Ypsilanti AR, Akiyama JA, Mannion BJ, Plajzer-Frick I, Novak CS, Harrington AN, Pham QT, Kato M, Zhu Y, Godoy J, Meky E, Hunter RD, Shi M, Kvon EZ, Afzal V, Tran S, Rubenstein JLR, Visel A, Pennacchio LA, Dickel DE. Snetkova V, et al. Nat Genet. 2021 Apr;53(4):521-528. doi: 10.1038/s41588-021-00812-3. Epub 2021 Mar 29. Nat Genet. 2021. PMID: 33782603 Free PMC article.

References

    1. Siepel, A. et al. Genome Res 15, 1034–1050 (2005). - DOI
    1. Zoonomia Consortium. Nature 587, 240–245 (2020). - DOI
    1. Snetkova, V. et al. Nat. Genet. https://doi.org/10.1038/s41588-021-00812-3 (2021).
    1. Levine, M. Curr. Biol. 20, R754–R763 (2010). - DOI
    1. Osterwalder, M. et al. Nature 554, 239–243 (2018). - DOI

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