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. 2021 Jul;15(7):741-752.
doi: 10.1111/crj.13356. Epub 2021 Mar 29.

Fatigue: A forgotten symptom of asthma

Fatma Esra Günaydın  1 , Dane Ediger  1 , Müge Erbay  1
Affiliations

Fatigue: A forgotten symptom of asthma

Fatma Esra Günaydın et al. Clin Respir J. 2021 Jul.

Abstract

Objective: Fatigue is a common symptom frequently reported in many disorders but little is known about the prevalence of fatigue in asthma. The objective of this study was to determine the prevalence of fatigue in asthmatic patients, the effect of fatigue on asthma quality of life and the relationship between fatigue and anxiety/depression MATERIALS AND METHODS: This prospective cross-sectional study was conducted in Uludağ University Faculty of Medicine, Department of Immunology and Allergic Diseases outpatient clinic from June 2019 to December 2019. Fatigue was assessed using the Checklist Individual Strength-Fatigue (CIS-Fatigue), psychological distress was assessed using the Beck Depression Inventory (BDI) and the Beck Anxiety Inventory (BAI) and quality of life were assessed using the Asthma Quality of Life Questionnaire (AQLQ).

Results: In the present study, a total of 168 patients are included with an average age of 43.8 ± 4.3 years. Nearly 64.8% of patients had controlled asthma and (35.2%) patients had uncontrolled asthma. Fatigue (CIS-Fatigue ≥ 27 points) was detected in 62.6% of patients and associated with asthma-related quality of life, asthma control, dyspnea, depression and anxiety (P < 0.05). However, the degree of lung function impairment and asthma severity were not associated with fatigue.

Conclusions: Fatigue as a symptom is common in asthmatic patients and correlates with asthma-related quality of life, asthma control, dyspnea, depression and anxiety. Future studies are needed to better understand the physical, psychological, behavioural and systemic factors that precipitate or perpetuate fatigue in asthma.

Keywords: anxiety; asthma; depression; dyspnea; fatigue; prevalence; quality of life.

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References

    1. Global Strategy for Asthma Management and Prevention 2020 Report [online. Accessed September 1, 2020. Website: https://ginasthma.org/wp-content/uploads/2020/06/GINA-2020-report_20_06_....
    1. Masoli M, Fabian D, Holt S, Beasley R. Global Initiative for Asthma (GINA) program: the global burden of asthma: executive summary of the GINA dissemination committee report. Allergy. 2004;59(5):469-478.
    1. Van Herck M, Spruit M, Burtin C, et al. Fatigue is highly prevalent in patients with asthma and contributes to the burden of disease. J Clin Med. 2018;7:471.
    1. Rudell K, Hareendran A, Bonner N, et al. Patients' experience of asthma control and clinical guidelines: perspectives from a qualitative study. Respir Med. 2012;106(6):909-911.
    1. Svedsater H, Roberts J, Patel C, et al. Life impact and treatment preferences of individuals with asthma and chronic obstructive pulmonary disease: results from qualitative interviews and focus groups. Adv Ther. 2017;34(6):1466-1481.