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. 2021:1261:137-151.
doi: 10.1007/978-981-15-7360-6_11.

Xanthophyllomyces dendrorhous, a Versatile Platform for the Production of Carotenoids and Other Acetyl-CoA-Derived Compounds

Gerhard Sandmann  1 , Hendrik Pollmann  2 , Sören Gassel  2 , Jürgen Breitenbach  2
Affiliations

Xanthophyllomyces dendrorhous, a Versatile Platform for the Production of Carotenoids and Other Acetyl-CoA-Derived Compounds

Gerhard Sandmann et al. Adv Exp Med Biol. 2021.

Abstract

Xanthophyllomyces dendrorhous (with Phaffia rhodozyma as its anamorphic state) is a basidiomycetous, moderately psychrophilic, red yeast belonging to the Cystofilobasidiales. Its red pigmentation is caused by the accumulation of astaxanthin, which is a unique feature among fungi. The present chapter reviews astaxanthin biosynthesis and acetyl-CoA metabolism in X. dendrorhous and describes the construction of a versatile platform for the production of carotenoids, such as astaxanthin, and other acetyl-CoA-derived compounds including fatty acids by using this fungus.

Keywords: Astaxanthin; Basidiomycete; Carotenoid biosynthesis; Poly-unsaturated fatty acids; Xanthophyllomyces dendrorhous.

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