CRISPR-based pathogenic fungal genome editing for control of infection and disease

Abstract

Fungi play important roles in many aspects of human life, such as in various food, beverage, agricultural, chemical, and pharmaceutical industries. Meanwhile, some fungal species cause several severe diseases in plants, humans and animals. Fungal and fungal-like diseases pose a severe threat to human health, food security, and ecosystem health worldwide. This chapter introduces CRISPR-based genome editing technologies for pathogenic fungi and their application in controlling fungal diseases.

Keywords: Animal pathogen; CRISPR/Cas system; Disease control; Fungi; Genome editing; Human pathogen; Plant pathogen.