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Review
. 2021 May;361(5):567-574.
doi: 10.1016/j.amjms.2021.01.023. Epub 2021 Feb 4.

Literature Review of COVID-19, Pulmonary and Extrapulmonary Disease

Fariba Yazdanpanah  1 , Akash Garg  1 , Shahrad Shadman  2 , Hamid Yazdanpanah Asmarz  3
Affiliations
Review

Literature Review of COVID-19, Pulmonary and Extrapulmonary Disease

Fariba Yazdanpanah et al. Am J Med Sci. 2021 May.

Abstract

In December 2019 novel coronavirus-Severe Acute Respiratory Syndrome-Corona Virus2 (SARS-CoV2)-originated from Wuhan, China, and spread rapidly around the world. This literature review highlights the dynamic nature of COVID-19 transmission and presentation. Analyzing 59 relevant articles up to May 1st, 2020 reflects that the main reported clinical manifestation of COVID-19 pandemic is fever and respiratory involvement. Also, current literature demonstrates a wide spectrum of different and atypical presentation(s) of COVID-19. The definite route of SARS-CoV2 transmission is respiratory droplets, however, virus nucleic acid has been detected in the stool and urine specimens as well. The severity of symptoms and outcomes of COVID-19 vary based on the patient's medical background, age, sex, and concurrent medical conditions (e.g. pregnancy). This is the first review that classifies all essential points regarding COVID-19 manifestations at a glance to improve the outcome of the patients by a better insight into diagnosis and management.

Keywords: COVID-19; Manifestations; Novel corona virus (2019-ncov); Presentations; Severe acute respiratory syndrome-corona virus2 (sars-cov2); Transmission.

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Figures

Figure 1
Figure 1
Different types of Human Coronaviruses (HCoVs).
See this image and copyright information in PMC

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