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Comment
. 2021 May;22(5):265.
doi: 10.1038/s41576-021-00357-5.

Stem cells root out genetic variants

Joseph Willson  1
Affiliations
Comment

Stem cells root out genetic variants

Joseph Willson. Nat Rev Genet. 2021 May.
No abstract available

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Comment on

  • Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation.
    Jerber J, Seaton DD, Cuomo ASE, Kumasaka N, Haldane J, Steer J, Patel M, Pearce D, Andersson M, Bonder MJ, Mountjoy E, Ghoussaini M, Lancaster MA; HipSci Consortium; Marioni JC, Merkle FT, Gaffney DJ, Stegle O. Jerber J, et al. Nat Genet. 2021 Mar;53(3):304-312. doi: 10.1038/s41588-021-00801-6. Epub 2021 Mar 4. Nat Genet. 2021. PMID: 33664506 Free PMC article.
  • Identification of rare and common regulatory variants in pluripotent cells using population-scale transcriptomics.
    Bonder MJ, Smail C, Gloudemans MJ, Frésard L, Jakubosky D, D'Antonio M, Li X, Ferraro NM, Carcamo-Orive I, Mirauta B, Seaton DD, Cai N, Vakili D, Horta D, Zhao C, Zastrow DB, Bonner DE; HipSci Consortium; iPSCORE consortium; Undiagnosed Diseases Network; PhLiPS consortium; Wheeler MT, Kilpinen H, Knowles JW, Smith EN, Frazer KA, Montgomery SB, Stegle O. Bonder MJ, et al. Nat Genet. 2021 Mar;53(3):313-321. doi: 10.1038/s41588-021-00800-7. Epub 2021 Mar 4. Nat Genet. 2021. PMID: 33664507 Free PMC article.

References

Original article
    1. Jerber, J. et al. Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation. Nat. Genet. 53, 304–312 (2021) - DOI
    1. Bonder, M. J. et al. Identification of rare and common regulatory variants in pluripotent cells using population-scale transcriptomics. Nat. Genet. 53, 313–321 (2021) - DOI

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