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. 2021 Jan 3;10(2):134-138.
doi: 10.1007/s13691-020-00462-y. eCollection 2021 Apr.

Experience of the pancreas duodenectomy for so-called carcinosarcoma of the common bile duct:a case report and review of literature

Suguru Sasamoto  1 , Takeshi Aoki  1 , Yoshihiko Tashiro  1 , Kazuhiro Matsuda  1 , Tomotake Koizumi  1 , Tomokazu Kusano  1 , Yusuke Wada  1 , Hideki Shibata  1 , Kodai Tomioka  1 , Takeshi Yamashita  1 , Hiromi Date  1 , Tomotake Ariyoshi  1 , Satoru Goto  1 , Kimiyasu Yamazaki  1 , Akira Fujimori  1 , Makoto Watanabe  1 , Yuta Enami  1 , Koji Otsuka  1 , Tomoko Norose  2 , Nobuyuki Ohike  2 , Toshiko Yamochi  2 , Masafumi Takimoto  2 , Masahiko Murakami  1
Affiliations

Experience of the pancreas duodenectomy for so-called carcinosarcoma of the common bile duct:a case report and review of literature

Suguru Sasamoto et al. Int Cancer Conf J. .

Abstract

A 79-year-old man presented with malaise and jaundice at a local hospital. His blood tests showed severe inflammation, liver failure, and high expression of several tumour markers. Radiological findings revealed dilated common and intrahepatic bile ducts and a lower bile duct constricted by a soft tissue mass. Histological findings by endoscopy showed a suspected adenocarcinoma, which was determined as class IV by cytology. The patient was referred to our hospital for surgical treatment. He underwent pancreaticoduodenectomy and the final diagnosis was so-called carcinosarcoma of the bile duct. He had liver metastasis and died at 26 postoperative months.

Keywords: Bile duct cancer; Carcinosarcoma of common bile duct; Case report; Pancreaticoduodenectomy.

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Conflict of interest statement

Conflict of interestThere are no financial or other interests in the submitted manuscript that might be construed as a conflict of interest.

Figures

Fig. 1
Fig. 1
Preoperative abdominal CT, MRI. Contrast CT showing dilated common and intrahepatic bile ducts (a) and a constricted lower bile duct by a soft tissue mass with contrast (b, white arrow c:zoomed lesion). T2-weighted magnetic resonance cholangiopancreatography showing a low-intensity area of the distal bile duct (white arrow) and dilated common and intrahepatic bile ducts(d, e:zoomed lesion, f:coronal view)
Fig. 2
Fig. 2
Preoperative ERCP and Resected specimen and microscopic findings. Endoscopic retrograde cholangiopancreatography showing dilated common and intrahepatic bile ducts and a constricted lower bile duct (white arrow) (a: before inserting stent, b: after). (c) Macroscopic findings of the resected specimen showed a nodular-infiltrating tumour at the distal part of the common bile duct of 1.3 × 1.8 cm in size. (d) Microscopic specimen findings. Middle-low differentiated adenocarcinoma and sarcomatoid tissue were localised in a single tumour (haematoxylin and eosin staining, magnification × 2). (e) Immunohistological staining revealed that both the sarcomatous and carcinomatous areas were positive for epithelial markers (cytokeratin AE1/3 stain, magnification × 10). (f) Vimentin staining revealed that both the sarcomatous area was weakly positive (Vimentin stain, magnification × 10)
Fig. 3
Fig. 3
Postoperative abdominal CT (9 month after surgery). (a) Contrast CT showing a mass with a contrasted edge at liver Segment 7/6 that was suspected of liver metastasis (white arrow)
See this image and copyright information in PMC

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