Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Mar;25(3):327-330.
doi: 10.5005/jp-journals-10071-23766.

Melioidosis in a Tertiary Care Center from South India: A 5-year Experience

Affiliations

Melioidosis in a Tertiary Care Center from South India: A 5-year Experience

Vithiya Ganesan et al. Indian J Crit Care Med. 2021 Mar.

Abstract

The present study was done with the objective to know the clinical presentation, microbiological features, and treatment outcome of melioidosis patients in our hospital, which is an emerging infection in India, and to know the differences in clinical course and outcome between bacteremic and nonbacteremic patients. This retrospective observational study was carried out over a period of 5 years from January 2015 to December 2019. Thirty-five cases of culture-confirmed melioidosis were identified with age range between 5 and 74 years. A large number of patients (n = 31) presented with uncontrolled diabetes mellitus. Six patients died of septic shock, and the outcome of eight patients was unknown as they were discharged against medical advice. There were no relapses observed. Melioidosis growing as a neglected tropical disease in India warrants awareness among all clinicians across the country. How to cite this article: Ganesan V, Murugan M, Sundaramurthy R, Soundaram GVG. Melioidosis in a Tertiary Care Center from South India: A 5-year Experience. Indian J Crit Care Med 2021;25(3):327-330.

Keywords: Melioidosis; Neuromelioidosis; Osteomyelitis; Septicemia.

PubMed Disclaimer

Conflict of interest statement

Source of support: Nil Conflict of interest: None

Figures

Fig. 1
Fig. 1
MRI postcontrast T1W axial left sphenoidal and ethmoidal sinusitis with left cavernous sinus thrombosis and proptosis
Fig. 2
Fig. 2
MRI T2W and postcontrast T1W sagittal showing leptomeningitis with brainstem encephalitis and rim-enhancing abscess in brainstem extending into spinal cord with rim-enhancing intraspinal abscess

References

    1. Vijaykumar GS, Thilakavathy P, Jeremiah SS, Vithiya G. Osteomyelitis of humerus and intramuscular abscess due to melioidosis. Kathmandu Univ Med J. 2016;;14((54):):184––185.. PMID: 28166079. - PubMed
    1. Ganesan V, Sundaramoorthy R, Subramanian S. Melioidosis-series of seven cases from Madurai, Tamil Nadu, India. Indian J Crit Care Med. 2019;;23((3):):149––151.. doi: 10.5005/jp-journals-10071-23139. DOI: - DOI - PMC - PubMed
    1. Mukhopadhyay C, Shaw T, Varghese GM, Dance DAB. Melioidosis in South Asia (India, Nepal, Pakistan, Bhutan and Afghanistan). Trop Med Infect Dis. 2018;;3((2):):51.. doi: 10.3390/tropicalmed3020051. DOI: - DOI - PMC - PubMed
    1. Koshy M, Jagannati M, Ralph R, Victor P, David T, Sathyendra S et al. Clinical manifestations, antimicrobial drug susceptibility patterns, and outcomes in melioidosis cases, India. Emerg Infect Dis. 2019;;25((2):):316––320.. doi: 10.3201/eid2502.170745. DOI: - DOI - PMC - PubMed
    1. Wongwandee M, Linasmita P. Central nervous system melioidosis: a systematic review of individual participant data of case reports and case series. PLoS Negl Trop Dis. 2019;;13((4):):e0007320.. doi: 10.1371/journal.pntd.0007320. DOI: - DOI - PMC - PubMed

LinkOut - more resources