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. 2021 Apr;19(4):1123-1129.
doi: 10.1111/jth.15260.

International pediatric thrombosis network to advance pediatric thrombosis research: Communication from the ISTH SSC subcommittee on pediatric and neonatal thrombosis and hemostasis

C Heleen van Ommen  1 , Manuela Albisetti  2 , Mohir Bhatt  3 , Marianne Bonduel  4 , Brian Branchford  5 , Elizabeth Chalmers  6 , Anthony Chan  3 , Neil A Goldenberg  7   8 , Susanne Holzhauer  9 , Paul Monagle  10   11 , Ulrike Nowak-Göttl  12 , Shoshana Revel-Vilk  13 , Gabriela Sciuccatie  4 , Nongnuch Sirachainan  14 , Christoph Male  15 ; Subcommittee on Pediatric, Neonatal Thrombosis, Hemostasis
Affiliations

International pediatric thrombosis network to advance pediatric thrombosis research: Communication from the ISTH SSC subcommittee on pediatric and neonatal thrombosis and hemostasis

C Heleen van Ommen et al. J Thromb Haemost. 2021 Apr.

Abstract

Pediatric thromboembolism is a rare and heterogenous disease. As a result, there is a paucity of knowledge with regard to natural history, management, and outcomes of most types of pediatric venous and arterial thromboembolism. International research collaboration is needed to fill these knowledge gaps. Not only randomized controlled trials, but also representative observational studies are required to answer all research questions. Therefore, the ISTH SSC Subcommittee on Pediatric and Neonatal Thrombosis and Hemostasis initiated the International Pediatric Thrombosis Network (IPTN). The aims of the IPTN include (1) development of the Throm-PED registry to facilitate international prospective observational studies, and (2) establishment of a network of pediatric thrombosis centers experienced in effectively conducting clinical trials and observational studies. The IPTN needs dedicated clinicians all over the world and several funding sources to obtain high-quality research data to reach its ultimate goal of improving care in children with thrombosis. The aim of this communication is to call for active participation in the IPTN to all physicians taking care of children with thrombosis worldwide.

Keywords: network; observational; pediatric; registry; thromboembolism.

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Conflict of interest statement

We have no conflicts of interest to disclose.

Figures

FIGURE 1
FIGURE 1
Current structure of the International Pediatric Thrombosis Network (IPTN). The basic Throm‐PED registry collects data about all pediatric patients with venous and arterial thrombosis, including age, gender, location, risk factors, treatment, and short‐term outcome. Each member of the IPTN can propose substudies using the Throm‐PED registry. These substudies are discussed in the general assembly meeting, which takes place during the annual ISTH congress. The current open substudies are shown in the figure
See this image and copyright information in PMC

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