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. 2021 May;47(5):609-611.
doi: 10.1007/s00134-021-06375-5. Epub 2021 Apr 2.

Intra-cycle power: is the flow profile a neglected component of lung protection?

John J Marini  1 , Philip S Crooke  2 , Luciano Gattinoni  3
Affiliations

Intra-cycle power: is the flow profile a neglected component of lung protection?

John J Marini et al. Intensive Care Med. 2021 May.
No abstract available

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Conflict of interest statement

The authors affirm that none has a conflict of financial or other interest relevant to this work.

Figures

Fig. 1
Fig. 1
Hypothetical intracycle elastic (‘alveolar’) and total power curves as mathematically modeled functions of the elapsed inspiratory time (t) during a single inflation to the same tidal volume for 5 flow profiles: constant (CF), decelerating (DF), sinusoidal (Sin), accelerating (AF) pressure control (Pset). These modes are compared for typical clinical values simulating severe ARDS (a, b) and severe COPD (c, d), and a hypothetical threshold level (dashed line) demarcates the lower boundary of VILI risk. Note that for each patient type, marked numerical differences separate instantaneous total and elastic power values, as well as the flow-driven power profiles (Zero PEEP is assumed)
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Comment in

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