Empowering MYC carcinogenesis via RNA loops
- PMID: 33798412
- DOI: 10.1016/j.molcel.2021.03.011
Empowering MYC carcinogenesis via RNA loops
Abstract
Cieśla et al. (2021) uncover intricate circuits of post-transcriptional regulation induced by the Myc oncogene, including alternative splicing and translational control, which are relevant for breast cancer prognosis and contribute to metabolic reprogramming and stem cell-like features of cancer cells.
Copyright © 2021 Elsevier Inc. All rights reserved.
Comment on
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Oncogenic translation directs spliceosome dynamics revealing an integral role for SF3A3 in breast cancer.Mol Cell. 2021 Apr 1;81(7):1453-1468.e12. doi: 10.1016/j.molcel.2021.01.034. Epub 2021 Mar 3. Mol Cell. 2021. PMID: 33662273
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