doi: 10.1016/0145-2126(88)90061-6.
Production of an active urokinase by leukemia cells: a novel distinction from cell lines of solid tumors
Affiliations
- PMID: 3379974
- DOI: 10.1016/0145-2126(88)90061-6
Item in Clipboard
Production of an active urokinase by leukemia cells: a novel distinction from cell lines of solid tumors
Leuk Res.
1988.
Abstract
A new screening test is described which enabled rapid determination of the proportion of single-chain and two-chain urokinase produced in the culture supernatants of 18 human cell lines. A clear distinction was found between two groups of cell lines: cells derived from ten solid tumors produced almost exclusively single-chain proenzyme, while the majority of the enzyme found in cultures of eight leukemia cell lines was in the active, two-chain form.