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. 2021 Mar 8;10(5):1130.
doi: 10.3390/jcm10051130.

Association between Sudden Sensorineural Hearing Loss and Lyme Disease

Klaudia Sowula  1 , Joanna Szaleniec  1 , Kamila Stolcman  1 , Piotr Ceranowicz  2 , Sebastian Kocoń  1 , Jerzy Tomik  1
Affiliations

Association between Sudden Sensorineural Hearing Loss and Lyme Disease

Klaudia Sowula et al. J Clin Med. .

Abstract

Objectives: Sudden sensorineural hearing loss (SSNHL) is defined as sensorineural hearing loss of 30 dB or more over at least three adjacent audiometric frequencies occurring within a 72-h period of time. One of the causes of SSNHL could be the progressive inflammatory state caused by an infection. The aim of this study was to assess the prevalence of SSNHL caused by various factors, most importantly those potentially related to Lyme disease.

Material and methods: The study includes a group of 86 patients between the ages of 20 and 70 who were hospitalized due to SSNHL between 2017 and 2018. All of these patients underwent a detailed medical interview and an otolaryngological examination, including audiological and diagnostic tests. Additionally, ELISA and Western blot tests were performed to confirm the diagnosis of Lyme disease.

Results: In this group of 86 patients, nine patients presented with positive antibodies toward Borrelia burgdorferi sensu lato. This group was treated with antibiotics and experienced partial or complete regression of their deafness. This may suggest a relationship between SSNHL and Lyme disease.

Conclusion: Infections caused by Borrelia burgdorferi may contribute to the development of inflammatory and angiopathic lesions, which are a possible cause of SSNHL. The longer the duration of the infection, the greater the likelihood of permanent and irreversible changes in the vessels of the cochlea or auditory nerve. Therefore, serological tests for Borrelia burgdorferi should be performed during the diagnosis of SSNHL as a possible cause of this illness.

Keywords: Borrelia burgdorferi; Lyme disease; auditory nerve; sudden sensorineural hearing loss.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Reasons for sudden deafness in the examined group of patients (AT—two patients, VNC—four patients, PRBB—nine patients, ISSNHL—71 patients).
See this image and copyright information in PMC

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