Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 Apr;8(4):1677-83.
doi: 10.1128/mcb.8.4.1677-1683.1988.

Regulation of c-myb expression in human neuroblastoma cells during retinoic acid-induced differentiation

C J Thiele  1 , P S Cohen, M A Israel
Affiliations

Regulation of c-myb expression in human neuroblastoma cells during retinoic acid-induced differentiation

C J Thiele et al. Mol Cell Biol. 1988 Apr.

Abstract

We detected expression of the c-myb proto-oncogene, which was initially thought to be expressed in a tissue-specific manner in cells of hematopoietic lineage, in human tissues of neuronal origin. Since the level of c-myb expression declined during fetal development, we studied the regulation of its expression in human neuroblastoma cell lines induced to differentiate by retinoic acid. The expression of c-myb declined during the maturation of neuroblastoma cells, and this change was mediated by a decrease in c-myb transcription.

PubMed Disclaimer

References

    1. Mol Cell Biol. 1982 Jun;2(6):617-24 - PubMed
    1. Virology. 1961 Oct;15:185-99 - PubMed
    1. Natl Cancer Inst Monogr. 1976 Nov;44:49-54 - PubMed
    1. J Mol Biol. 1977 Jun 15;113(1):237-51 - PubMed
    1. Biochemistry. 1978 May 30;17(11):2198-205 - PubMed

LinkOut - more resources