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Review
. 2021 Mar 2;26(5):1335.
doi: 10.3390/molecules26051335.

The Pluripotent Activities of Caffeic Acid Phenethyl Ester

Batoryna Olgierd  1 , Żyła Kamila  1 , Banyś Anna  2 , Morawiec Emilia  3   4   5
Affiliations
Review

The Pluripotent Activities of Caffeic Acid Phenethyl Ester

Batoryna Olgierd et al. Molecules. .

Abstract

Caffeic acid phenethyl ester (CAPE) is a strong antioxidant extracted from honey bee-hive propolis. The mentioned compound, a well-known NF-κB inhibitor, has been used in traditional medicine as a potent anti-inflammatory agent. CAPE has a broad spectrum of biological properties including anti-viral, anti-bacterial, anti-cancer, immunomodulatory, and wound-healing activities. This review characterizes published data about CAPE biological properties and potential therapeutic applications, that can be used in various diseases.

Keywords: NF-κB; antioxidant; caffeic acid phenethyl ester (CAPE); inflammation; propolis.

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Conflict of interest statement

The authors declare that there are no conflicts of interest.

Figures

Figure 1
Figure 1
Chemical structure of caffeic acid phenethyl ester [3].
Figure 2
Figure 2
Healing stages [57].
See this image and copyright information in PMC

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