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Review
. 2021 Mar 9;10(5):1146.
doi: 10.3390/jcm10051146.

Ischemic Stroke and Heart Failure: Facts and Numbers. An Update

Anush Barkhudaryan  1   2 , Wolfram Doehner  3   4   5 , Nadja Scherbakov  3   4   5
Affiliations
Review

Ischemic Stroke and Heart Failure: Facts and Numbers. An Update

Anush Barkhudaryan et al. J Clin Med. .

Abstract

Heart failure (HF) is a severe clinical syndrome accompanied by a number of comorbidities. Ischemic stroke occurs frequently in patients with HF as a complication of the disease. In the present review, we aimed to summarize the current state of research on the role of cardio-cerebral interactions in the prevalence, etiology, and prognosis of both diseases. The main pathophysiological mechanisms underlying the development of stroke in HF and vice versa are discussed. In addition, we reviewed the results of recent clinical trials investigating the prevalence and prevention of stroke in patients with HF.

Keywords: HFpEF; HFrEF; cardio–cerebral interactions; ischemic stroke; risk factor; stroke prevention.

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Conflict of interest statement

The authors have no conflict of interest to declare.

Figures

Figure 1
Figure 1
The comorbidities and risk factors in ischemic stroke and heart failure.
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