Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2021 Mar 31;10(4):772.
doi: 10.3390/cells10040772.

Introduction of Mouse Embryonic Fibroblasts into Early Embryos Causes Reprogramming and (Con)fusion

Pierre Savatier  1
Affiliations
Editorial

Introduction of Mouse Embryonic Fibroblasts into Early Embryos Causes Reprogramming and (Con)fusion

Pierre Savatier. Cells. .

Abstract

The reprogramming of somatic cell nuclei to achieve pluripotency is one of the most important biological discoveries of the last few decades [...].

PubMed Disclaimer

Conflict of interest statement

The author declares no conflict of interest.

Comment in

Comment on

References

    1. Wilmut I., Schnieke A.E., McWhir J., Kind A.J., Campbell K.H. Viable offspring derived from fetal and adult mammalian cells. Nature. 1997;385:810–813. doi: 10.1038/385810a0. - DOI - PubMed
    1. Munsie M.J., Michalska A.E., O’Brien C.M., Trounson A.O., Pera M.F., Mountford P.S. Isolation of pluripotent embryonic stem cells from reprogrammed adult mouse somatic cell nuclei. Curr. Biol. 2000;10:989–992. doi: 10.1016/S0960-9822(00)00648-5. - DOI - PubMed
    1. Tada M., Takahama Y., Abe K., Nakatsuji N., Tada T. Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells. Curr. Biol. 2001;11:1553–1558. doi: 10.1016/S0960-9822(01)00459-6. - DOI - PubMed
    1. Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006;126:663–676. doi: 10.1016/j.cell.2006.07.024. - DOI - PubMed
    1. Ying Q.L., Nichols J., Evans E.P., Smith A.G. Changing potency by spontaneous fusion. Nature. 2002;416:545–548. doi: 10.1038/nature729. - DOI - PubMed

LinkOut - more resources