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Review
. 2021 Mar 30;10(7):1390.
doi: 10.3390/jcm10071390.

Biologics for Psoriasis during the COVID-19 Pandemic

Affiliations
Review

Biologics for Psoriasis during the COVID-19 Pandemic

Koji Kamiya et al. J Clin Med. .

Abstract

Psoriasis is a chronic, immune-mediated inflammatory disease that predominantly affects the skin and joints. The recent therapeutic development for psoriasis has been remarkable and biologics have dramatically changed the treatment of psoriasis. In moderate-to-severe cases, systemic therapies are required to control their symptoms and biologics can provide greater efficacy when compared with other types of therapies. The coronavirus disease (COVID-19) pandemic has had a great impact on the lives of many people and has worsened substantially worldwide. During the ongoing COVID-19 pandemic, it still remains unclear whether biologics suppress the immune system and increase the risk of COVID-19. In this review, we have summarized the experience with biologics used for treating psoriasis during the COVID-19 pandemic. Biologics seem to be beneficial to COVID-19 infection. Shared decision-making that is based on updated information is highlighted in the time of COVID-19.

Keywords: COVID-19; SARS-CoV-2; biologics; psoriasis; systemic therapy.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Biologics for psoriasis and COVID-19. Tumor necrosis factor (TNF) inhibitors and interleukin (IL)-17 inhibitors have the potential to prevent the infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the cytokine storm of COVID-19.

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