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Review
. 2021 Mar 19;11(3):548.
doi: 10.3390/diagnostics11030548.

Forgotten No More-The Role of Right Ventricular Dysfunction in Heart Failure with Reduced Ejection Fraction: An Echocardiographic Perspective

Aura Vijiiac  1   2 , Sebastian Onciul  1   2 , Claudia Guzu  2 , Alina Scarlatescu  2 , Ioana Petre  1   2 , Diana Zamfir  2 , Roxana Onut  2 , Silvia Deaconu  1   2 , Maria Dorobantu  1   2
Affiliations
Review

Forgotten No More-The Role of Right Ventricular Dysfunction in Heart Failure with Reduced Ejection Fraction: An Echocardiographic Perspective

Aura Vijiiac et al. Diagnostics (Basel). .

Abstract

During the last decade, studies have raised awareness of the crucial role that the right ventricle plays in various clinical settings, including diseases primarily linked to the left ventricle. The assessment of right ventricular performance with conventional echocardiography is challenging. Novel echocardiographic techniques improve the functional assessment of the right ventricle and they show good correlation with the gold standard represented by cardiac magnetic resonance. This review summarizes the traditional and innovative echocardiographic techniques used in the functional assessment of the right ventricle, focusing on the role of right ventricular dysfunction in heart failure with reduced ejection fraction and providing a perspective on recent evidence from literature.

Keywords: heart failure with reduced ejection fraction; myocardial strain; right ventricle; three-dimensional echocardiography.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Calculation of right ventricular myocardial performance index (RV MPI) using the tissue Doppler imaging (TDI) method. RV—right ventricle; MPI—myocardial performance index; TDI—tissue Doppler imaging; ICT—isovolumic contraction time; ET—ejection time; IRT—isovolumic relaxation time; TCT—total contraction time.
Figure 2
Figure 2
Calculation of RIVA using TDI. RIVA—right isovolumic acceleration; TDI—tissue Doppler imaging; IVV—isovolumic velocity; AT—acceleration time.
Figure 3
Figure 3
Six-segment model of longitudinal RV strain using STE. RV—right ventricle; STE—speckle-tracking echocardiography.
Figure 4
Figure 4
3D assessment of RV volumes and ejection fraction using dedicated software. 3D—three dimensional; RV—right ventricle.
See this image and copyright information in PMC

References

    1. Vos T., Flaxman A.D., Naghavi M., Lozano R., Michaud C., Ezzati M., Shibuya K., Salomon J.A., Abdalla S., Aboyans V., et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380:2163–2196. doi: 10.1016/S0140-6736(12)61729-2. - DOI - PMC - PubMed
    1. Virani S.S., Alonso A., Benjamin E.J., Bittencourt M.S., Callaway C.W., Carson A.P., Chamberlain A.M., Chang A.R., Cheng S., Delling F.N., et al. Heart Disease and Stroke Statistics—2020 Update; A Report from the American Heart Association. Circulation. 2020;141:e139–e596. doi: 10.1161/CIR.0000000000000757. - DOI - PubMed
    1. Heidenreich P.A., Albert N.M., Allen L.A., Bluemke D.A., Butler J., Fonarow G.C., Ikonomidis J.S., Khavjou O., Konstam M.A., Maddox T.M., et al. Forecasting the impact of heart failure in the United States: A policy statement from the American Heart Association. Circ. Heart Fail. 2013;6:606–619. doi: 10.1161/HHF.0b013e318291329a. - DOI - PMC - PubMed
    1. Ponikowski P., Voors A.A., Anker S.D., Buneo H., Cleland J.G.F., Coats A.J.S., Falk V., González-Juanatey J.R., Harjola V., Jankowska E.A., et al. 2016 ESC Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure of the European Society of Cardiology (ESC) Eur. J. Heart Fail. 2016;18:891–975. doi: 10.1002/ejhf.592. - DOI - PubMed
    1. Pocock S.J., Ariti C.A., McMurray J.J., Maggioni A., Køber L., Squire I.B., Swedberg K., Dobson J., Poppe K.K., Whalley G.A., et al. Meta-Analysis Global Group in Chronic Heart Failure. Predicting Survival in Heart Failure: A Risk Score Based on 39,372 Patients from 30 Studies. Eur. Heart J. 2013;34:1404–1413. doi: 10.1093/eurheartj/ehs337. - DOI - PubMed

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