Mannosidosis in a litter of Persian cats
- PMID: 3381451
- DOI: 10.1136/vr.122.15.351
Mannosidosis in a litter of Persian cats
Abstract
Three kittens in a litter of Persian cats showed, from the age of eight weeks, tremor, ataxia, dysmetria, progressive weakness and emaciation. Cytoplasmic vacuolation was observed in neurons, mesenchymal and epithelial cells of tissues taken post mortem. The alpha-mannosidase activity of brain tissue of one cat tested was 4.8 per cent of control values and the urine of two cats contained large amounts of mannose-rich oligosaccharides.
Similar articles
-
The clinical and pathologic heterogeneity of feline alpha-mannosidosis.J Vet Intern Med. 1988 Oct-Dec;2(4):163-70. doi: 10.1111/j.1939-1676.1988.tb00311.x. J Vet Intern Med. 1988. PMID: 3230555
-
Oligosaccharides from placenta: early diagnosis of feline mannosidosis.FEBS Lett. 1986 Jan 20;195(1-2):247-52. doi: 10.1016/0014-5793(86)80169-7. FEBS Lett. 1986. PMID: 3943609
-
Characterization of alpha-mannosidase in feline mannosidosis.J Inherit Metab Dis. 1988;11(1):3-16. doi: 10.1007/BF01800052. J Inherit Metab Dis. 1988. PMID: 3128686
-
Mammalian beta-D-mannosidase and beta-mannosidosis.Biochimie. 1992 Jan;74(1):5-11. doi: 10.1016/0300-9084(92)90179-i. Biochimie. 1992. PMID: 1576208 Review.
-
[Mannosidosis. Clinical and enzymatic studies in a family].Neurologia. 1986 Mar-Apr;1(2):58-62. Neurologia. 1986. PMID: 3079111 Review. Spanish. No abstract available.
Cited by
-
Different oligosaccharides accumulate in the brain and urine of a cat with alpha-mannosidosis: structure determination of five brain-derived and seventeen urinary oligosaccharides.Glycoconj J. 1991 Feb;8(1):17-28. doi: 10.1007/BF00731639. Glycoconj J. 1991. PMID: 1668528
-
Dried blood spots for the enzymatic diagnosis of lysosomal storage diseases in dogs and cats.Vet Clin Pathol. 2012 Dec;41(4):548-57. doi: 10.1111/j.1939-165x.2012.00485.x. Epub 2012 Nov 2. Vet Clin Pathol. 2012. PMID: 23121383 Free PMC article.
-
Inherited metabolic disease in companion animals: searching for nature's mistakes.Vet J. 2007 Sep;174(2):252-9. doi: 10.1016/j.tvjl.2006.08.017. Epub 2006 Nov 7. Vet J. 2007. PMID: 17085062 Free PMC article. Review.
-
Apparent diffusion coefficient reveals gray and white matter disease, and T2 mapping detects white matter disease in the brain in feline alpha-mannosidosis.AJNR Am J Neuroradiol. 2008 Feb;29(2):308-13. doi: 10.3174/ajnr.A0791. Epub 2007 Nov 1. AJNR Am J Neuroradiol. 2008. PMID: 17974615 Free PMC article.
-
Purification of feline lysosomal alpha-mannosidase, determination of its cDNA sequence and identification of a mutation causing alpha-mannosidosis in Persian cats.Biochem J. 1997 Dec 15;328 ( Pt 3)(Pt 3):863-70. doi: 10.1042/bj3280863. Biochem J. 1997. PMID: 9396732 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Miscellaneous