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Review
. 2021 Aug;94(2):e13041.
doi: 10.1111/sji.13041. Epub 2021 Apr 4.

Pituitary neuropeptides and B lymphocyte function

Affiliations
Free article
Review

Pituitary neuropeptides and B lymphocyte function

Ann L Benko et al. Scand J Immunol. 2021 Aug.
Free article

Abstract

This review discusses the accumulated evidence that pro-opiomelanocortin (POMC) gene products as well as other pituitary neuropeptides derived from related genes (Proenkephalin, PENK; Prodynorphin, PDYN, and Pronociceptin, PNOC) can exert direct effects on B lymphocytes to modulate their functions. We also review the available data on receptor systems that might be involved in the transmission of such hormonal signals to B cells.

Keywords: B cells; antibodies/immunoglobulins; human.

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References

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