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Comment
. 2021 Apr 5;21(3):15357597211004568.
doi: 10.1177/15357597211004568. Online ahead of print.

Guardians of the Frequency: Neuronal Regulation by Microglia

Sara Eyal
Comment

Guardians of the Frequency: Neuronal Regulation by Microglia

Sara Eyal. Epilepsy Curr. .

Abstract

[Box: see text].

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Comment on

  • Microglial Gi-dependent dynamics regulate brain network hyperexcitability.
    Merlini M, Rafalski VA, Ma K, Kim KY, Bushong EA, Rios Coronado PE, Yan Z, Mendiola AS, Sozmen EG, Ryu JK, Haberl MG, Madany M, Sampson DN, Petersen MA, Bardehle S, Tognatta R, Dean T Jr, Acevedo RM, Cabriga B, Thomas R, Coughlin SR, Ellisman MH, Palop JJ, Akassoglou K. Merlini M, et al. Nat Neurosci. 2021 Jan;24(1):19-23. doi: 10.1038/s41593-020-00756-7. Epub 2020 Dec 14. Nat Neurosci. 2021. PMID: 33318667 Free PMC article.

References

    1. Cserép C, Pósfai B, Dénes Á. Shaping neuronal fate: functional heterogeneity of direct microglia-neuron interactions. Neuron. 2021;109(2):222–240. - PubMed
    1. Umpierre AD, Wu LJ. How microglia sense and regulate neuronal activity. Glia. 2020;69(7):1637–1653. doi: 10.1002/glia.23961 - PMC - PubMed
    1. Wyatt-Johnson SK, Brewster AL. Emerging roles for microglial phagocytic signaling in epilepsy. Epilepsy Curr. 2020;20(1):33–38. - PMC - PubMed
    1. Vezzani A. Brain inflammation and seizures: evolving concepts and new findings in the last 2 decades. Epilepsy Curr. 2020;20(6_suppl):40s–43s. - PMC - PubMed
    1. Haynes SE, Hollopeter G, Yang G, et al. The P2Y12 receptor regulates microglial activation by extracellular nucleotides. Nat Neurosci. 2006;9(12):1512–1519. - PubMed

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