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Review
. 2021 Jun 30;30(2):115-123.
doi: 10.7570/jomes20098.

Oxytocin: A Potential Therapeutic for Obesity

Soo Min Hong  1 , Jeong-Kyung Ko  2 , Jung-Joon Moon  3 , Youl-Ri Kim  2   4
Affiliations
Review

Oxytocin: A Potential Therapeutic for Obesity

Soo Min Hong et al. J Obes Metab Syndr. .

Abstract

Oxytocin is a neuropeptide involved in the homeostasis of food consumption and energy; it affects hedonic eating. Studies in obese or binge-eating patients reported the hypophagic effect of oxytocin, which reduced caloric intake after administration. Several studies have demonstrated the effect of oxytocin's increasing energy intake, decreasing food consumption, and contributing to weight loss. Oxytocin's effects on food intake and metabolism suggest its therapeutic potential for treating obesity and binge eating.

Keywords: Obesity; Oxytocin; Therapeutics.

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Conflict of interest statement

CONFLICTS OF INTEREST

The authors declare no conflict of interest.

Figures

Figure. 1
Figure. 1
Oxytocin production and secretion in the central nervous system. SON, supraoptic nucleus; PVN, paraventricular nucleus.
Figure. 2
Figure. 2
The effect of oxytocin on eating behavior and metabolism.
See this image and copyright information in PMC

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