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. 2021 Jun:34:100774.
doi: 10.1016/j.ijcha.2021.100774. Epub 2021 Mar 31.

Temporal relation between second dose BNT162b2 mRNA Covid-19 vaccine and cardiac involvement in a patient with previous SARS-COV-2 infection

Enrico Ammirati  1 , Cristina Cavalotti  1 , Angela Milazzo  1 , Patrizia Pedrotti  1 , Francesco Soriano  1 , Jan W Schroeder  2 , Nuccia Morici  1 , Cristina Giannattasio  1   3 , Maria Frigerio  1 , Marco Metra  4 , Paolo G Camici  5 , Fabrizio Oliva  1
Affiliations

Temporal relation between second dose BNT162b2 mRNA Covid-19 vaccine and cardiac involvement in a patient with previous SARS-COV-2 infection

Enrico Ammirati et al. Int J Cardiol Heart Vasc. 2021 Jun.
No abstract available

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Coronary angiography and cardiac MRI. (A) The right coronary artery only had a mild plaque (<30% luminal diameter) in the mid portion, while (B) left main stem, left anterior descending artery and circumflex artery had no evidence of coronary plaques. (C) T2- weighted 3-chamber view on cardiac MRI, showing focal areas of edema involving the subepicardial-intramyocardial regions of the basal and apical segments of the infero-lateral wall (arrows). (D) Late gadolinium enhancement confirmed the presence of non-ischemic myocardial lesions in the basal and apical segments of the infero-lateral wall (arrows) consistent with acute myocarditis.
See this image and copyright information in PMC

References

    1. Shi S., Qin M., Shen B., Cai Y., Liu T., Yang F. Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China. JAMA Cardiol. 2020;5(7):802–810. - PMC - PubMed
    1. Guo T., Fan Y., Chen M., Wu X., Zhang L., He T. Cardiovascular implications of fatal outcomes of patients with coronavirus disease 2019 (COVID-19) JAMA Cardiol. 2020;5(7):811–818. - PMC - PubMed
    1. Li C., Jiang J., Wang F., Zhou N., Veronese G., Moslehi J.J. Longitudinal correlation of biomarkers of cardiac injury, inflammation, and coagulation to outcome in hospitalized COVID-19 patients. J. Mol. Cell Cardiol. 2020;147:74–87. - PMC - PubMed
    1. Inciardi R.M., Lupi L., Zaccone G., Italia L., Raffo M., Tomasoni D. Cardiac involvement in a patient with coronavirus disease 2019 (COVID-19) JAMA Cardiol. 2020;5(7):819–824. - PMC - PubMed
    1. Polack F.P., Thomas S.J., Kitchin N., Absalon J., Gurtman A., Lockhart S. Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine. N Engl. J. Med. 2020;383(27):2603–2615. - PMC - PubMed