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. 1988 Apr;23(4):360-4.
doi: 10.1002/ana.410230408.

Successful chemotherapy for recurrent malignant oligodendroglioma

J G Cairncross  1 , D R Macdonald
Affiliations

Successful chemotherapy for recurrent malignant oligodendroglioma

J G Cairncross et al. Ann Neurol. 1988 Apr.

Abstract

Eight consecutive patients with recurrent malignant oligodendroglioma were treated with systemic chemotherapy. Six patients received a combination of procarbazine, lomustine (CCNU), and vincristine; 1 received carmustine (BCNU), and 1 diaziquone. All responded by clinical and computed tomographic scan criteria. One patient had a complete response for 78 weeks, and 7 patients had unequivocal partial responses lasting 30+ to 68+ weeks. Two partial responders had complete control of systemic metastases. Malignant oligodendroglioma is a uniquely chemosensitive glial tumor.

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