Immunonutrition in head and neck cancer patients undergoing chemoradiotherapy: an alternative approach for overcoming potential bias

Affiliations

¹ From the Clinical Nutrition and Dietetics Unit, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Policlinico San Matteo, Pavia, Italy.
² National Center of Oncological Hadrontherapy (Fondazione CNAO), Pavia, Italy.
³ Radiation Oncology Department, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Policlinico San Matteo, and the University of Pavia Italy, Pavia, Italy.
⁴ Cell Factory and Pediatric Hematology Oncology, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Policlinico San Matteo, Pavia, Italy.
⁵ Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, ASST (Azienda Socio Sanitaria Territoriale) Spedali Civili, Brescia, Italy.
⁶ Medical Oncology Unit, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Policlinico San Matteo, Pavia, Italy.
⁷ Internal Medicine Department, University of Pavia, Pavia, Italy.

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Riccardo Caccialanza et al. Am J Clin Nutr. 2021.

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. 2021 Apr 6;113(4):1053-1054.

doi: 10.1093/ajcn/nqaa421.

¹ From the Clinical Nutrition and Dietetics Unit, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Policlinico San Matteo, Pavia, Italy.
² National Center of Oncological Hadrontherapy (Fondazione CNAO), Pavia, Italy.
³ Radiation Oncology Department, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Policlinico San Matteo, and the University of Pavia Italy, Pavia, Italy.
⁴ Cell Factory and Pediatric Hematology Oncology, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Policlinico San Matteo, Pavia, Italy.
⁵ Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, ASST (Azienda Socio Sanitaria Territoriale) Spedali Civili, Brescia, Italy.
⁶ Medical Oncology Unit, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Policlinico San Matteo, Pavia, Italy.
⁷ Internal Medicine Department, University of Pavia, Pavia, Italy.

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Reply to Caccialanza et al.
Boisselier P, Thézénas S, Flori N, Vinches M, Bourhis J, Senesse P. Boisselier P, et al. Am J Clin Nutr. 2021 Apr 6;113(4):1054-1055. doi: 10.1093/ajcn/nqaa425. Am J Clin Nutr. 2021. PMID: 33822866 No abstract available.

A double-blind phase III trial of immunomodulating nutritional formula during adjuvant chemoradiotherapy in head and neck cancer patients: IMPATOX.
Boisselier P, Kaminsky MC, Thézenas S, Gallocher O, Lavau-Denes S, Garcia-Ramirez M, Alfonsi M, Cupissol D, de Forges H, Janiszewski C, Geoffrois L, Sire C, Senesse P; Head and Neck Oncology and Radiotherapy Group (GORTEC). Boisselier P, et al. Am J Clin Nutr. 2020 Dec 10;112(6):1523-1531. doi: 10.1093/ajcn/nqaa227. Am J Clin Nutr. 2020. PMID: 32936874 Clinical Trial.