Prodromal Parkinson disease - time is brain
- PMID: 33824494
- DOI: 10.1038/s41582-021-00489-6
Prodromal Parkinson disease - time is brain
Comment on
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Detection of α-synuclein in CSF by RT-QuIC in patients with isolated rapid-eye-movement sleep behaviour disorder: a longitudinal observational study.Lancet Neurol. 2021 Mar;20(3):203-212. doi: 10.1016/S1474-4422(20)30449-X. Lancet Neurol. 2021. PMID: 33609478
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- Postuma, R. B. et al. Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study. Brain 142, 744–759 (2019). - DOI
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- Iranzo, A. et al. Detection of α-synuclein in CSF by RT-QuIC in patients with isolated rapid-eye-movement sleep behaviour disorder: a longitudinal observational study. Lancet Neurol. 20, 203–212 (2021). - DOI
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- Fairfoul, G. et al. Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies. Ann. Clin. Transl Neurol. 3, 812–818 (2016). - DOI
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- Shahnawaz, M. et al. Development of a biochemical diagnosis of parkinson disease by detection of α-synuclein misfolded aggregates in cerebrospinal fluid. JAMA Neurol. 74, 163–172 (2017). - DOI
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