Correction: Helminth Colonization Is Associated with Increased Diversity of the Gut Microbiota

Abstract

[This corrects the article DOI: 10.1371/journal.pntd.0002880.].

Fig 1. Abundance and diversity in the intestinal microbiome in 51 Malaysian subjects.

(Panel A) The number of observed OTUs plotted against age for 49 individual samples. The number of observed OTUs for most samples was between 1500–4000. (Panel B) Relative abundance of the top phyla represented across the 51 subjects arranged by increasing age. The abundance patterns were largely similar across the individual subjects, except in two of the younger subjects who had high abundance of Actinobacteria (Bifidobacterium sp.) in their stool samples.

Fig 2. Beta and alpha diversity for the 51 subjects.

(Panel A) PCoA of the microbial communities in helminth-positive and helminth-negative samples. Clustering of helminth-positive subjects could be observed, which is statistically significant (p  =  0.04). Rarefaction curves calculated for phylogenetic distance (Panel B) and Shannon index (Panel C) demonstrating the higher microbial diversity found among helminth positive subjects. (Panel D) Alpha diversity metrics (observed OTUs, Phylogenetic Diversity and Shannon Index) were compared between helminth positive (n = 34) and negative (n = 15) individuals. Analysis methods are detailed in the original publication. Two individual samples with < 1000 sequencing reads were removed from the alpha diversity analysis. * p < 0.05 by non-parametric two-sample t-test as implemented in QIIME compare_alpha_diversity.py.