Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2021 Apr 6;33(4):707-708.
doi: 10.1016/j.cmet.2021.03.013.

New scavenger to fine-tune insulin action in β cells

Catherine Hall  1 , Eunhee Choi  2
Affiliations
Free article
Comment

New scavenger to fine-tune insulin action in β cells

Catherine Hall et al. Cell Metab. .
Free article

Abstract

Insulin receptor signaling is crucial for β cell homeostasis. In a recent issue of Nature, Ansarullah et al. (2021) have identified the insulin inhibitory receptor (inceptor), which balances insulin signaling by promoting insulin receptor internalization.

PubMed Disclaimer

Conflict of interest statement

Declaration of interests The authors declare no competing interests.

Comment on

  • Inceptor counteracts insulin signalling in β-cells to control glycaemia.
    Ansarullah, Jain C, Far FF, Homberg S, Wißmiller K, von Hahn FG, Raducanu A, Schirge S, Sterr M, Bilekova S, Siehler J, Wiener J, Oppenländer L, Morshedi A, Bastidas-Ponce A, Collden G, Irmler M, Beckers J, Feuchtinger A, Grzybek M, Ahlbrecht C, Feederle R, Plettenburg O, Müller TD, Meier M, Tschöp MH, Coskun Ü, Lickert H. Ansarullah, et al. Nature. 2021 Feb;590(7845):326-331. doi: 10.1038/s41586-021-03225-8. Epub 2021 Jan 27. Nature. 2021. PMID: 33505018

LinkOut - more resources