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Case Reports
. 2021 Apr 7;14(4):e239887.
doi: 10.1136/bcr-2020-239887.

Neurofibroma of the hard palate

Bethany Cartwright  1 , Kenneth Corsar  2
Affiliations
Case Reports

Neurofibroma of the hard palate

Bethany Cartwright et al. BMJ Case Rep. .

Abstract

Neurofibromas are defined as benign tumours arising from peripheral nerve sheaths. Few intraoral palatal cases have been reported. Neurofibromas can occur as part of neurofibromatosis, type 1 (NF1) or type 2 (NF2). A 41-year-old patient presented with a slowly enlarging soft tissue mass on the hard palate. An incisional biopsy was performed, which confirmed the diagnosis of a neurofibroma associated with NF1. It should be considered that there is a chance of malignant transformation. Here, we discuss the clinical features, types, diagnosis, histopathology and treatment options.

Keywords: dentistry and oral medicine; head and neck surgery; oral and maxillofacial surgery.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
A photograph depicting multiple skin-coloured nodular masses on the patients head and neck region.
Figure 2
Figure 2
A photograph depicting brownish macules on the patient’s forehead, suggestive of café au lait spots.
Figure 3
Figure 3
An intraoral photograph demonstrating the soft tissue mass on the hard palate.
Figure 4
Figure 4
Histopathology slide demonstrating the polypoid piece of palatal mucosa containing an ill-defined dermal lesion.
Figure 5
Figure 5
Histopathology slide demonstrating bland spindled cells within a loose fibrous stroma with scattered mast cells.
See this image and copyright information in PMC

References

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