Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Apr 7;11(1):7671.
doi: 10.1038/s41598-021-87252-5.

A lower maximum bite force is a risk factor for developing cardiovascular disease: the Suita study

Sakae Hashimoto  1 , Takayuki Kosaka  2 , Michikazu Nakai  3 , Momoyo Kida  1 , Shuri Fushida  1 , Yoshihiro Kokubo  4 , Makoto Watanabe  4 , Aya Higashiyama  5 , Kazunori Ikebe  1 , Takahiro Ono  1   6 , Yoshihiro Miyamoto  3
Affiliations

A lower maximum bite force is a risk factor for developing cardiovascular disease: the Suita study

Sakae Hashimoto et al. Sci Rep. .

Abstract

Decreases in masticatory function are believed to be related to the development of cardiovascular disease (CVD) through inappropriate nutritional intake. This study focused on maximum bite force (MBF), which is an objective, quantitative index of masticatory function, and its association with the development of CVD (stroke and coronary heart disease) was investigated. The subjects were 1547 participants of the Suita study with no history of CVD who underwent medical and dental health examinations between June 2008 and June 2013. In addition to undergoing a basic physical examination at baseline, their MBF was measured. They subsequently underwent follow-up surveys for the development of CVD (mean follow-up, 3.5 years). The association between baseline MBF and the development of CVD was investigated by multivariate adjustment using a Cox proportional hazards model. CVD developed in 32 subjects during follow-up. The trend test showed a significant association between baseline MBF and CVD in a model that combined men and women. When analysed by sex, the trend test found a significant association between baseline MBF and CVD in women. Low MBF, which is an objective and quantitative index of masticatory function, may be a risk factor for the development of CVD.

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Flow chart of study participants. CVD, cardiovascular disease.
See this image and copyright information in PMC

References

    1. Preventing chronic disease: a vital investment. World Health Organization 2005.
    1. Blaizot A, Vergnes JN, Nuwwareh S, et al. Periodontal diseases and cardiovascular events: meta-analysis of observational studies. Int. Dent. J. 2009;59:197–209. - PubMed
    1. Lockhart PB, Bolger AF, Papapanou PN, et al. Periodontal disease and atherosclerotic vascular disease: does the evidence support an independent association? Circulation. 2012;125:2520–2544. doi: 10.1161/CIR.0b013e31825719f3. - DOI - PubMed
    1. Holmlund A, Holm G, Lind L. Number of teeth as a predictor of cardiovascular mortality in a cohort of 7,674 subjects followed for 12 years. J. Periodontol. 2010;81:870–876. doi: 10.1902/jop.2010.090680. - DOI - PubMed
    1. Liljestrand JM, Havulinna AS, Paju S, et al. Missing teeth predict incident cardiovascular events, diabetes, and death. J. Dent. Res. 2015;94:1055–1062. doi: 10.1177/0022034515586352. - DOI - PubMed

Publication types

LinkOut - more resources