Neonatal outcomes during the COVID-19 pandemic in New York City

doi:10.1038/s41390-021-01513-7

. 2022 Feb;91(3):477-479.

doi: 10.1038/s41390-021-01513-7. Epub 2021 Apr 7.

Neonatal outcomes during the COVID-19 pandemic in New York City

Felix Richter^#^{1

2}, Arielle S Strasser^#^{1

2}, Mayte Suarez-Farinas¹, Shan Zhao^{2

3}, Girish N Nadkarni^{2

4

5}, Ethylin Wang Jabs^{1

6}, Katherine Guttmann⁷, Benjamin S Glicksberg^{8

9}

Affiliations

¹ Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
² The Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
³ Department of Anesthesiology, Perioperative and Pain Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
⁴ Department of Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
⁵ Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
⁶ Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
⁷ Division of Newborn Medicine, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
⁸ Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York City, NY, USA. benjamin.glicksberg@mssm.edu.
⁹ The Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York City, NY, USA. benjamin.glicksberg@mssm.edu.

^# Contributed equally.

PMID: 33828229
PMCID: PMC8025442
DOI: 10.1038/s41390-021-01513-7

Neonatal outcomes during the COVID-19 pandemic in New York City

Felix Richter et al. Pediatr Res. 2022 Feb.

. 2022 Feb;91(3):477-479.

doi: 10.1038/s41390-021-01513-7. Epub 2021 Apr 7.

Authors

Affiliations

¹ Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
² The Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
³ Department of Anesthesiology, Perioperative and Pain Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
⁴ Department of Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
⁵ Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
⁶ Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
⁷ Division of Newborn Medicine, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.
⁸ Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York City, NY, USA. benjamin.glicksberg@mssm.edu.
⁹ The Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York City, NY, USA. benjamin.glicksberg@mssm.edu.

^# Contributed equally.

PMID: 33828229
PMCID: PMC8025442
DOI: 10.1038/s41390-021-01513-7

No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

**Fig. 1. Comparable changes to previous years in preterm birth and NICU admission rates at the Mount Sinai Hospital after New York City (NYC) implemented lockdown measures.**
a Change in the percent of preterm births (GA < 37 weeks) (top panel) and NICU admissions (bottom panel) in the 3 months before and after the implementation of COVID-19 lockdown measures (March 16, 2020), compared to those of the same time periods in 2012–2019. b Results of the difference-in-difference (DiD) logistic regression that compared the odds ratios (ORs) in 2020 to those in 2012–2019. ORs represent changes in neonatal outcomes after lockdown measures. We observed P_DiD > 0.05 for all time windows, indicating that changes in both neonatal outcomes were comparable in 2020 to the same time periods in prior years. OR odds ratio, 95% CI 95% confidence interval (lower-upper), β_DID DiD coefficient, P_DID p value of the DiD coefficient.

**Fig. 2. Statistically significant reduction in preterm birth and NICU admission rates after the initiation of NYC phase one reopening compared to 2012–2019.**
a Change in the percent of preterm births (top panel) and NICU admissions (bottom panel) in the 2.75 months before and after NYC phase one reopening (June 8, 2020), compared to those of the same time periods in 2012–2019. b Results of the difference-in-difference (DiD) logistic regression that compared the odds ratios (ORs) in 2020 to those in 2012–2019. ORs represent changes in neonatal outcomes after reopening. We observed β_DID < 0 and P_DiD < 0.05 in preterm birth rates for all time windows, and the largest time window for NICU admissions, indicating that both neonatal outcomes decreased significantly after reopening when compared to same time periods in prior years. OR odds ratio, 95% CI 95% confidence interval (lower-upper), β_DID DiD coefficient, P_DID p value of the DiD coefficient.

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References

1. Quealy, K. The richest neighborhoods emptied out most as coronavirus hit New York City. The New York Times (2020).
1. Been JV, et al. Impact of COVID-19 mitigation measures on the incidence of preterm birth: a national quasi-experimental study. Lancet Public Health. 2020;5:e604–e611. doi: 10.1016/S2468-2667(20)30223-1. - DOI - PMC - PubMed
1. Hedermann G, et al. Danish premature birth rates during the COVID-19 lockdown. Arch. Dis. Child Fetal Neonatal Ed. 2020;106:93–95. doi: 10.1136/archdischild-2020-319990. - DOI - PMC - PubMed
1. Philip RK, et al. Unprecedented reduction in births of very low birthweight (VLBW) and extremely low birthweight (ELBW) infants during the COVID-19 lockdown in Ireland: a ‘natural experiment’ allowing analysis of data from the prior two decades. BMJ Glob. Health. 2020;5:e003075. doi: 10.1136/bmjgh-2020-003075. - DOI - PMC - PubMed
1. Maeda, Y. et al. Trends in intensive neonatal care during the COVID-19 outbreak in Japan. Arch. Dis. Child Fetal Neonatal Ed. 10.1136/archdischild-2020-320521 (2020). - PubMed

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[1] Quealy, K. The richest neighborhoods emptied out most as coronavirus hit New York City. The New York Times (2020).

[2] Quealy, K. The richest neighborhoods emptied out most as coronavirus hit New York City. The New York Times (2020).

[3] Been JV, et al. Impact of COVID-19 mitigation measures on the incidence of preterm birth: a national quasi-experimental study. Lancet Public Health. 2020;5:e604–e611. doi: 10.1016/S2468-2667(20)30223-1. - DOI - PMC - PubMed

[4] Been JV, et al. Impact of COVID-19 mitigation measures on the incidence of preterm birth: a national quasi-experimental study. Lancet Public Health. 2020;5:e604–e611. doi: 10.1016/S2468-2667(20)30223-1. - DOI - PMC - PubMed

[5] Hedermann G, et al. Danish premature birth rates during the COVID-19 lockdown. Arch. Dis. Child Fetal Neonatal Ed. 2020;106:93–95. doi: 10.1136/archdischild-2020-319990. - DOI - PMC - PubMed

[6] Hedermann G, et al. Danish premature birth rates during the COVID-19 lockdown. Arch. Dis. Child Fetal Neonatal Ed. 2020;106:93–95. doi: 10.1136/archdischild-2020-319990. - DOI - PMC - PubMed

[7] Philip RK, et al. Unprecedented reduction in births of very low birthweight (VLBW) and extremely low birthweight (ELBW) infants during the COVID-19 lockdown in Ireland: a ‘natural experiment’ allowing analysis of data from the prior two decades. BMJ Glob. Health. 2020;5:e003075. doi: 10.1136/bmjgh-2020-003075. - DOI - PMC - PubMed

[8] Philip RK, et al. Unprecedented reduction in births of very low birthweight (VLBW) and extremely low birthweight (ELBW) infants during the COVID-19 lockdown in Ireland: a ‘natural experiment’ allowing analysis of data from the prior two decades. BMJ Glob. Health. 2020;5:e003075. doi: 10.1136/bmjgh-2020-003075. - DOI - PMC - PubMed

[9] Maeda, Y. et al. Trends in intensive neonatal care during the COVID-19 outbreak in Japan. Arch. Dis. Child Fetal Neonatal Ed. 10.1136/archdischild-2020-320521 (2020). - PubMed

[10] Maeda, Y. et al. Trends in intensive neonatal care during the COVID-19 outbreak in Japan. Arch. Dis. Child Fetal Neonatal Ed. 10.1136/archdischild-2020-320521 (2020). - PubMed

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Neonatal outcomes during the COVID-19 pandemic in New York City

Affiliations

Neonatal outcomes during the COVID-19 pandemic in New York City

Authors

Affiliations

Conflict of interest statement

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