Minding the Gap: Leveraging Mindfulness to Inform Cue Exposure Treatment for Substance Use Disorders
- PMID: 33828515
- PMCID: PMC8019935
- DOI: 10.3389/fpsyg.2021.649409
Minding the Gap: Leveraging Mindfulness to Inform Cue Exposure Treatment for Substance Use Disorders
Abstract
Despite extinction-based processes demonstrating efficacy in the animal extinction and human anxiety literatures, extinction for substance use disorders (SUD) has shown poor efficacy (i. e., cue exposure treatment [CET]). Reasons for this lack of success include common threats to extinction, such as renewal and reinstatement. In recent decades, research on mindfulness for SUD has flourished, and a key aspect of these mindfulness-based interventions includes teaching individuals to stay present with whatever experience they have, even if unpleasant, without trying to change/escape/avoid it. Similarly, CET teaches individuals to not escape/avoid conditioned responses (e.g., craving) by engaging in drug use behavior. This paper discusses how mindfulness-based research and practices could positively influence CET through future research (e.g., Could mindfulness practice attenuate renewal? Might mindfulness training + CET enhance the ability to extinguish the most salient or motivational cues?), with the long-term goal of improving SUD treatment.
Keywords: cue exposure; extinction; mindfulness; substance use disorder; treatment.
Copyright © 2021 Vinci, Sawyer and Yang.
Conflict of interest statement
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Similar articles
-
Mindfulness-based relapse prevention combined with virtual reality cue exposure for methamphetamine use disorder: Study protocol for a randomized controlled trial.Contemp Clin Trials. 2018 Jul;70:99-105. doi: 10.1016/j.cct.2018.04.006. Epub 2018 Apr 19. Contemp Clin Trials. 2018. PMID: 29679670 Clinical Trial.
-
Cue Exposure Therapy for Alcohol Use Disorders: What Can Be Learned from Exposure Therapy for Anxiety Disorders?Subst Use Misuse. 2019;54(12):2053-2063. doi: 10.1080/10826084.2019.1618328. Epub 2019 Jul 1. Subst Use Misuse. 2019. PMID: 31259660 Review.
-
Postretrieval Extinction Attenuates Alcohol Cue Reactivity in Rats.Alcohol Clin Exp Res. 2017 Mar;41(3):608-617. doi: 10.1111/acer.13323. Epub 2017 Feb 7. Alcohol Clin Exp Res. 2017. PMID: 28169439 Free PMC article.
-
Effects of D-cycloserine on extinction of mesolimbic cue reactivity in alcoholism: a randomized placebo-controlled trial.Psychopharmacology (Berl). 2015 Jul;232(13):2353-62. doi: 10.1007/s00213-015-3882-5. Epub 2015 Feb 21. Psychopharmacology (Berl). 2015. PMID: 25697860 Clinical Trial.
-
Mindfulness-Based Interventions for the Treatment of Aberrant Interoceptive Processing in Substance Use Disorders.Brain Sci. 2022 Feb 17;12(2):279. doi: 10.3390/brainsci12020279. Brain Sci. 2022. PMID: 35204042 Free PMC article. Review.
Cited by
-
Exploring the past, present, and future of the mindfulness field: A multitechnique bibliometric review.Front Psychol. 2022 Jul 26;13:792599. doi: 10.3389/fpsyg.2022.792599. eCollection 2022. Front Psychol. 2022. PMID: 35959046 Free PMC article.
-
Using augmented reality to deliver cue exposure treatment for smoking cessation: App usability findings and protocol for a randomized controlled trial.Contemp Clin Trials. 2025 Mar;150:107827. doi: 10.1016/j.cct.2025.107827. Epub 2025 Jan 27. Contemp Clin Trials. 2025. PMID: 39880329
-
What Happens When You Smoke a Cigarette Mindfully? A Deductive Qualitative Study.Mindfulness (N Y). 2022 Oct;13(10):2628-2640. doi: 10.1007/s12671-022-01984-7. Epub 2022 Sep 19. Mindfulness (N Y). 2022. PMID: 37692535 Free PMC article.
References
Publication types
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous