Prognostic factors in leptomeningeal metastases

Emilie Le Rhun^{1

2

3

4

5}, Patrick Devos^{6

7}, Johannes Weller⁸, Katharina Seystahl⁴, Francesca Mo⁹, Anette Compter¹⁰, Anna S Berghoff¹¹, Joost L M Jongen¹², Fabian Wolpert⁴, Roberta Rudà⁹, Dieta Brandsma¹⁰, Martin van den Bent¹², Matthias Preusser¹¹, Ulrich Herrlinger⁸, Michael Weller⁴

Affiliations

¹ University of Lille, Inserm, U-1192, Lille, France.
² Neuro-Oncology, General and Stereotaxic Neurosurgery Service, University Hospital of Lille, Rue Emile Laine, Lille Cedex, France.
³ Breast Cancer Department, Oscar Lambret Center, Lille Cedex, France.
⁴ Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.
⁵ Department of Neurosurgery, University Hospital and University of Zurich, Zurich, Switzerland.
⁶ Clinical Neuroscience Center and Comprehensive Cancer Center, University Hospital and University of Zurich, Zurich, Switzerland.
⁷ University of Lille, CHU Lille, ULR 2694 - METRICS: Évaluation des technologies de santé et des pratiques médicales, Lille, France.
⁸ Division of Clinical Neuro-Oncology, Department of Neurology, University Hospital Bonn, Venusberg Campus, Bonn, Germany.
⁹ Department of Neuro-Oncology, City of Health and Science University of Turin, Turin, Italy.
¹⁰ Department of Neuro-Oncology, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Amsterdam, the Netherlands.
¹¹ Department of Medicine I, Division of Oncology, Medical University of Vienna, Vienna, Austria.
¹² Brain Tumor Center at Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, the Netherlands.

Comment

Emilie Le Rhun et al. Neuro Oncol. 2021.

. 2021 Jul 1;23(7):1208-1209.

doi: 10.1093/neuonc/noab051.

¹ University of Lille, Inserm, U-1192, Lille, France.
² Neuro-Oncology, General and Stereotaxic Neurosurgery Service, University Hospital of Lille, Rue Emile Laine, Lille Cedex, France.
³ Breast Cancer Department, Oscar Lambret Center, Lille Cedex, France.
⁴ Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.
⁵ Department of Neurosurgery, University Hospital and University of Zurich, Zurich, Switzerland.
⁶ Clinical Neuroscience Center and Comprehensive Cancer Center, University Hospital and University of Zurich, Zurich, Switzerland.
⁷ University of Lille, CHU Lille, ULR 2694 - METRICS: Évaluation des technologies de santé et des pratiques médicales, Lille, France.
⁸ Division of Clinical Neuro-Oncology, Department of Neurology, University Hospital Bonn, Venusberg Campus, Bonn, Germany.
⁹ Department of Neuro-Oncology, City of Health and Science University of Turin, Turin, Italy.
¹⁰ Department of Neuro-Oncology, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Amsterdam, the Netherlands.
¹¹ Department of Medicine I, Division of Oncology, Medical University of Vienna, Vienna, Austria.
¹² Brain Tumor Center at Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, the Netherlands.

No abstract available

Comment on

Prognostic validation and clinical implications of the EANO ESMO classification of leptomeningeal metastasis from solid tumors.
Le Rhun E, Devos P, Weller J, Seystahl K, Mo F, Compter A, Berghoff AS, Jongen JLM, Wolpert F, Rudà R, Brandsma D, van den Bent M, Preusser M, Herrlinger U, Weller M. Le Rhun E, et al. Neuro Oncol. 2021 Jul 1;23(7):1100-1112. doi: 10.1093/neuonc/noaa298. Neuro Oncol. 2021. PMID: 33367859 Free PMC article.
The relevance of surgical status in nodular leptomeningeal metastasis patient outcomes.
Dankner M, Maritan SM. Dankner M, et al. Neuro Oncol. 2021 Jul 1;23(7):1207. doi: 10.1093/neuonc/noab035. Neuro Oncol. 2021. PMID: 33830265 Free PMC article. No abstract available.

1. Prabhu RS, Turner BE, Asher AL, et al. . A multi-institutional analysis of presentation and outcomes for leptomeningeal disease recurrence after surgical resection and radiosurgery for brain metastases. Neuro Oncol. 2019;21(8):1049–1059. - PMC - PubMed
1. Cagney DN, Lamba N, Sinha S, et al. . Association of neurosurgical resection with development of pachymeningeal seeding in patients with brain metastases. JAMA Oncol. 2019;5(5):703–709. - PMC - PubMed