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. 2021 Apr 15;184(8):1945-1948.
doi: 10.1016/j.cell.2021.03.019. Epub 2021 Apr 7.

The islet's bridesmaid becomes the bride: Proglucagon-derived peptides deliver transformative therapies

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The islet's bridesmaid becomes the bride: Proglucagon-derived peptides deliver transformative therapies

Stephen O'Rahilly. Cell. .
Free article

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Abstract

The 2021 Gairdner Prize is awarded to Daniel Drucker, Joel Habener, and Jens Juul Holst for the discovery of novel peptides encoded in the proglucagon sequence and the establishment of their physiological roles. These discoveries underpinned the development of therapeutics that are now benefiting patients with type 2 diabetes and other disorders worldwide.

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Conflict of interest statement

Declaration of interests S.O. provides or has provided remunerated consultancy services to a number of pharmaceutical and biotechnology companies including Pfizer, AstraZeneca Ltd., GSK, Novo-Nordisk, and ERX pharmaceuticals.

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