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Comment
. 2021 Sep 1;105(9):e94-e95.
doi: 10.1097/TP.0000000000003784.

Poor Anti-SARS-CoV-2 Humoral and T-cell Responses After 2 Injections of mRNA Vaccine in Kidney Transplant Recipients Treated With Belatacept

Nathalie Chavarot  1   2 , Amani Ouedrani  2   3   4 , Olivier Marion  5   6   7 , Marianne Leruez-Ville  2   8 , Estelle Vilain  1 , Maroua Baaziz  1   2 , Arnaud Del Bello  5   6   7 , Carole Burger  1   2 , Rebecca Sberro-Soussan  1   2 , Frank Martinez  1   2 , Lucienne Chatenoud  2   3   4 , Florence Abravanel  5   6   9 , Dany Anglicheau  1   2 , Jacques Izopet  5   6   9 , Chloé Couat  7 , Julien Zuber  1   2 , Christophe Legendre  1   2 , Fanny Lanternier  2   10 , Nassim Kamar  5   6   7 , Anne Scemla  1   2
Affiliations
Comment

Poor Anti-SARS-CoV-2 Humoral and T-cell Responses After 2 Injections of mRNA Vaccine in Kidney Transplant Recipients Treated With Belatacept

Nathalie Chavarot et al. Transplantation. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no funding or conflicts of interest.

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  • Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates.
    Walsh EE, Frenck RW Jr, Falsey AR, Kitchin N, Absalon J, Gurtman A, Lockhart S, Neuzil K, Mulligan MJ, Bailey R, Swanson KA, Li P, Koury K, Kalina W, Cooper D, Fontes-Garfias C, Shi PY, Türeci Ö, Tompkins KR, Lyke KE, Raabe V, Dormitzer PR, Jansen KU, Şahin U, Gruber WC. Walsh EE, et al. N Engl J Med. 2020 Dec 17;383(25):2439-2450. doi: 10.1056/NEJMoa2027906. Epub 2020 Oct 14. N Engl J Med. 2020. PMID: 33053279 Free PMC article. Clinical Trial.
  • BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans.
    Sahin U, Muik A, Vogler I, Derhovanessian E, Kranz LM, Vormehr M, Quandt J, Bidmon N, Ulges A, Baum A, Pascal KE, Maurus D, Brachtendorf S, Lörks V, Sikorski J, Koch P, Hilker R, Becker D, Eller AK, Grützner J, Tonigold M, Boesler C, Rosenbaum C, Heesen L, Kühnle MC, Poran A, Dong JZ, Luxemburger U, Kemmer-Brück A, Langer D, Bexon M, Bolte S, Palanche T, Schultz A, Baumann S, Mahiny AJ, Boros G, Reinholz J, Szabó GT, Karikó K, Shi PY, Fontes-Garfias C, Perez JL, Cutler M, Cooper D, Kyratsous CA, Dormitzer PR, Jansen KU, Türeci Ö. Sahin U, et al. Nature. 2021 Jul;595(7868):572-577. doi: 10.1038/s41586-021-03653-6. Epub 2021 May 27. Nature. 2021. PMID: 34044428 Clinical Trial.

References

    1. Walsh EE, Frenck RW Jr, Falsey AR, et al. Safety and immunogenicity of two RNA-based COVID-19 vaccine candidates. N Engl J Med. 2020;383:2439–2450.
    1. Sahin U, Muik A, Vogler I, et al. BNT162b2 induces SARS-CoV-2-neutralising antibodies and T cells in humans. medRxiv. Preprint. Posted online December 11, 2020. doi: 10.1101/2020.12.09.20245175. - DOI
    1. Boyarsky BJ, Werbel WA, Avery RK, et al. Immunogenicity of a single dose of SARS-CoV-2 messenger RNA vaccine in solid organ transplant recipients. JAMA. 2021;325:1784–1786.
    1. Ribeiro AC, Laurindo IM, Guedes LK, et al. Abatacept and reduced immune response to pandemic 2009 influenza A/H1N1 vaccination in patients with rheumatoid arthritis. Arthritis Care Res. 2013;65:476–480.
    1. Harritshøj LH, Gybel-Brask M, Afzal S, et al. Comparison of sixteen serological SARS-CoV-2 immunoassays in sixteen clinical laboratories. J Clin Microbiol. 2021;59:e02596-20.

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