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Observational Study
. 2021 Apr 9;100(14):e24673.
doi: 10.1097/MD.0000000000024673.

The effects of peripheral anterior synechiae on refractive outcomes after cataract surgery in eyes with primary angle-closure disease

Affiliations
Observational Study

The effects of peripheral anterior synechiae on refractive outcomes after cataract surgery in eyes with primary angle-closure disease

Tae-Eun Lee et al. Medicine (Baltimore). .

Abstract

Objective of the study was to investigate the effects of peripheral anterior synechiae (PAS) on refractive outcomes after cataract surgery in eyes with primary angle-closure disease (PACD).This is a retrospective, cross-sectional study. Seventy eyes of 70 PACD patients who underwent phacoemulsification and intraocular lens implantation. Patients were divided into 2 groups based on the presence of PAS on preoperative gonioscopy. The predictive power of the intraocular lens was calculated by the SRK/T, Hoffer Q, Haigis, and Holladay formulae. The mean absolute error (MAE) and predicted refractive errors were compared between PAS (+) and PAS (-) groups. We also evaluated the refractive errors with regards to the extent of PAS in the subanalyses.The mean MAE was greater in the PAS (+) group with all formulae (0.61-0.70 diopters [D] vs 0.33-0.45 D, all P < .05). The eyes with PAS tended towards myopia (-0.30 D to -0.51 D vs -0.05 D to +0.24 D, all P < .05). However, the MAEs or predicted refractive errors were not different, irrespective of the extent of PAS in the subanalyses (all, P > .05).The presence or absence of PAS may influence the postoperative refractive outcomes in PACD patients.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Possible mechanisms of refractive errors after cataract surgery in eyes with primary angle-closure with or without peripheral anterior synechiae (PAS) and representative images of anterior segment optical coherence tomography. (A) Eyes without PAS. (B) Eyes with PAS. Anterior chamber deepening was limited by PAS, consequently myopic shift could occur.

References

    1. Inoue T. Distribution and morphology of peripheral anterior synechia in primary angle-closure glaucoma. Nihon Ganka Gakkai Zasshi 1993;97:78–82. - PubMed
    1. Choi JS, Kim YY. Relationship between the extent of peripheral anterior synechiae and the severity of visual field defects in primary angle-closure glaucoma. Korean J Ophthalmol 2004;18:100–5. - PubMed
    1. Yang CH, Hung PT. Intraocular lens position and anterior chamber angle changes after cataract extraction in eyes with primary angle-closure glaucoma. J Cataract Refract Surg 1997;23:1109–13. - PubMed
    1. Hayashi K, Hayashi H, Nakao F, et al. Changes in anterior chamber angle width and depth after intraocular lens implantation in eyes with glaucoma. Ophthalmology 2000;107:698–703. - PubMed
    1. Ming Zhi Z, Lim ASM, Yin Wong T. A pilot study of lens extraction in the management of acute primary angle-closure glaucoma. Am J Ophthalmol 2003;135:534–6. - PubMed

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