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. 2021 Apr 13;118(15):e2105018118.
doi: 10.1073/pnas.2105018118.

News Feature: How "forever chemicals" might impair the immune system

Carolyn Beans

News Feature: How "forever chemicals" might impair the immune system

Carolyn Beans. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

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Animal models and human studies suggest that forever chemicals, delivered through water, food, and air, alter the immune system, potentially diminishing our ability to fight disease or respond to a vaccine. Image credit: Shutterstock/Dmitry Naumov.
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Although no longer in use, an aqueous fire-fighting foam containing a mixture of PFOA, PFOS, and other PFAS ingredients remains detectable in contaminated water. Image credit: Shutterstock/Bborriss.67.
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Researchers found that children in the Faroe Islands exposed via diet to PFAS chemicals experienced drops in antibody concentrations against tetanus and diphtheria, diseases that the children had been vaccinated against. Image credit: Shutterstock/Fexel.
See this image and copyright information in PMC

References

    1. Giesy J. P., Kannan K., Global distribution of perfluorooctane sulfonate in wildlife. Environ. Sci. Technol. 35, 1339–1342 (2001). - PubMed
    1. Berger U., Järnberg U., Kallenborn R., Perfluorinated alkylated substances (PFAS) in the European Nordic environment. Organohalogen Compd. 66, 3996–4002 (2004).
    1. National Institute of Environmental Health Sciences , Perfluoroalkyl and polyfluoroalkyl substances (PFAS) (2019). https://www.niehs.nih.gov/health/materials/perfluoroalkyl_and_polyfluoro.... Accessed 15 January 2021.
    1. Fenton S. E., et al. ., Per‐ and polyfluoroalkyl substance toxicity and human health review: Current state of knowledge and strategies for informing future research. Environ. Toxicol. Chem. 40, 606–630 (2021). - PMC - PubMed
    1. Lewis R. C., Johns L. E., Meeker J. D., Serum biomarkers of exposure to perfluoroalkyl substances in relation to serum testosterone and measures of thyroid function among adults and adolescents from NHANES 2011–2012. Int. J. Environ. Res. Public Health 12, 6098–6114 (2015). - PMC - PubMed

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