Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Mar 3;13(3):e13683.
doi: 10.7759/cureus.13683.

Pheochromocytoma Crisis in the Emergency Department

Affiliations
Case Reports

Pheochromocytoma Crisis in the Emergency Department

Stephanie R Bartikoski et al. Cureus. .

Abstract

Pheochromocytoma is a rare, often undiagnosed adrenal tumor that typically presents in early adulthood and is characterized by intermittent surges of catecholamines. While this "Great Mimic" may present with a variety of vague complaints such as headache, abdominal pain, or palpitations, it may also appear as a severely hypertensive patient with multi-organ failure and cardiopulmonary collapse known as pheochromocytoma crisis. Management of hypertensive emergency in these patients is unique, and the associated metabolic derangements, coagulopathy, thromboembolic events, and risk of adrenal capsule rupture add significant complexity, morbidity, and mortality to these cases. Emergency providers should learn when to suspect this uncommon but life-threatening diagnosis in order to properly manage these potentially critically ill patients.

Keywords: adrenal tumor; hypertensive emergency; phentolamine; pheochromocytoma; pheochromocytoma crisis; pulmonary edema; pulmonary embolism.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Left adrenal mass measuring 6.5 cm

References

    1. Pheochromocytoma. Farrugia FA, Charalampopoulos A. Endocrin Regul. 2019;53:191–212. - PubMed
    1. Clinical evaluation and treatment of pheochromocytoma. Davidson AS, Jones DM, Ruthven S, Helliwell T, Shore SL. Ann Clin Biochem. 2018;55:34–48. - PubMed
    1. Phaeochromocytoma crisis. Whitelaw BC, Prague JK, Mustafa OG, et al. Clin Endocrinol. 2014;80:13–22. - PubMed
    1. Westfall TC, Westfall DP. Goodman and Gilman's: The Pharmacological Basis of Therapeutics. Vol. 12. New York: McGraw Hill; 2011. Adrenergic agonists and antagonists; p. 309.
    1. Perioperative management of pheochromocytoma. Naranjo J, Dodd S, Martin Y. J Cardiothorac Vasc Anesth. 2017;31:1427–1439. - PubMed

Publication types

LinkOut - more resources