Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jan-Dec:20:1534735420975853.
doi: 10.1177/1534735420975853.

Preoperative Physical Activity Predicts Surgical Outcomes Following Lung Cancer Resection

Andrea Billé  1   2 , James Buxton  1 , Alessandro Viviano  1 , David Gammon  1 , Lukacs Veres  1 , Tom Routledge  1 , Karen Harrison-Phipps  1 , Allison Dixon  1 , Marco A Minetto  3
Affiliations

Preoperative Physical Activity Predicts Surgical Outcomes Following Lung Cancer Resection

Andrea Billé et al. Integr Cancer Ther. 2021 Jan-Dec.

Abstract

Objectives: To assess whether preoperative levels of physical activity predict the incidence of post-operative complications following anatomical lung resection.

Methods: Levels of physical activity (daily steps) were measured for 15 consecutive days using pedometers in 90 consecutive patients (prior to admission). Outcomes measured were cardiac and respiratory complications, length of stay, and 30-day re-admission rate.

Results: A total of 78 patients' datasets were analysed (12 patients were excluded due to non-compliance). Based on steps performed they were divided into quartiles; 1 (low physical activity) to 4 (high physical activity). There were no significant differences in age, smoking history, COPD, BMI, percentage predicted FEV1 and KCO and cardiovascular risk factors between the groups. There were significantly fewer total complications in quartiles 3 and 4 (high physical activity) compared to quartiles 1 and 2 (low physical activity) (8 vs 22; P = .01). There was a trend (P > .05) towards shorter hospital length of stay in quartiles 3 and 4 (median values of 4 and 5 days, respectively) compared to quartiles 1 and 2 (6 days for both groups).

Conclusions: Preoperative physical activity can help to predict postoperative outcome and can be used to stratify risk of postoperative complications and to monitor impact of preoperative interventions, ultimately improving short term outcomes.

Keywords: daily step; pedometer; performance status; lung cancer; physical activity.

PubMed Disclaimer

Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Patient enrollment flowchart and division into 4 groups according to the preoperative physical activity levels.
Figure 2.
Figure 2.
Bar chart displaying average daily steps by each subject. Quartiles of physical activity are delineated by different colors.
See this image and copyright information in PMC

References

    1. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68:394-424. - PubMed
    1. Møller H, Coupland VH, Tataru D, et al.. Geographical variations in the use of cancer treatments are associated with survival of lung cancer patients. Thorax. 2018;73:530-537. - PMC - PubMed
    1. Howington JA, Blum MG, Chang AC, Balekian AA, Murthy SC. Treatment of stage I and II non-small cell lung cancer: diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2013;143(suppl 5):e278S-e313S. - PubMed
    1. Palma D, Visser O, Lagerwaard FJ, Belderbos J, Slotman B, Senan S. Treatment of stage I NSCLC in elderly patients: a population-based matched-pair comparison of stereotactic radiotherapy versus surgery. Radiother Oncol. 2011;101:240-244. - PubMed
    1. Lim E, Baldwin D, Beckles M, et al.. Guidelines on the radical management of patients with lung cancer. Thorax. 2010;65(suppl 3):iii1-27. - PubMed

Publication types