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Comment
. 2021 Apr 9;6(1):146.
doi: 10.1038/s41392-021-00589-1.

Landscapes of SARS-CoV-2-reactive CD8+ T cells: heterogeneity of host immune responses against SARS-CoV-2

June-Young Koh  1 , Eui-Cheol Shin  2   3
Affiliations
Comment

Landscapes of SARS-CoV-2-reactive CD8+ T cells: heterogeneity of host immune responses against SARS-CoV-2

June-Young Koh et al. Signal Transduct Target Ther. .
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1. Single-cell RNA sequencing of virus-specific CD8+ T cells.
a Total CD8+ T cells include CD8+ T cells with various antigen specificity. b, c Virus-specific CD8+ T cells are fluorescently detected by activation-induced markers, such as CD69 and CD137, following ex vivo stimulation with viral antigens (b) or MHC-I multimer staining (c). d Virus-specific CD8+ T cells are enriched by sorting fluorescently stained cells. The procedure enriching activation-induced marker+ cells is called antigen-reactive T-cell enrichment (ARTE). e Enriched virus-specific CD8+ T cells are analyzed by single-cell RNA sequencing, and single-cell heterogeneity is revealed
See this image and copyright information in PMC

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References

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