[Antiviral and anti-inflammatory therapies in COVID-19]
- PMID: 33838023
- DOI: 10.1556/650.2021.32230
[Antiviral and anti-inflammatory therapies in COVID-19]
Abstract
Összefoglaló. Az új típusú koronavírus-fertőzés (COVID-19) nagy terhet ró az egészségügyi ellátórendszerre és a társadalomra. A betegségnek három nagy szakasza van, melyek alapvetően meghatározzák a kezelést. Az I-IIA fázisban az antivirális, míg a IIB-III. fázisban a gyulladásgátló kezelés áll előtérben, melyhez intenzív terápiás, szupportív kezelés csatlakozik. A jelen ajánlás kizárólag a gyógyszeres kezelésre vonatkozik, és a rendelkezésre álló bizonyítékok alapján foglalja össze a terápiás lehetőségeket. Emellett egy javasolt kezelési algoritmust is tartalmaz. Orv Hetil. 2021; 162(17): 643-651. Summary. The novel coronavirus infection (COVID-19) places a heavy burden on the health care system and our society. There are three major stages in the disease that fundamentally determine treatment approaches. Phases I-IIA require primarily antiviral treatment. In phases IIB-III, anti-inflammatory treatment is needed accompanied by intensive and supportive care. This recommendation applies only to pharmacotherapy and summarizes the therapeutic options based on the available evidence. It also includes a proposed treatment algorithm. Orv Hetil. 2021; 162(17): 643-651.
Keywords: Janus kinase inhibition; Janus-kináz-gátlás; antiviral treatment; antivirális kezelés; citokingátló kezelés; citokinvihar; coronavirus; corticosteroid; cytokine inhibition treatment; cytokine storm; interleukin-6 inhibition; interleukin-6-gátlás; intravenous immunoglobulin; intravénás immunglobulin; koronavírus; kortikoszteroid; novel coronavirus infection (COVID-19); új típusú koronavírus-fertőzés (COVID–19).
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