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Review
. 2020 Oct-Dec;36(4):435-442.
doi: 10.4103/joacp.JOACP_359_20. Epub 2020 Oct 26.

Systemic manifestations of COVID-19

Rubina K Mahajan  1 , Gunchan Paul  1 , Ramit Mahajan  2 , Parshotam L Gautam  1 , Birinder Paul  3
Affiliations
Review

Systemic manifestations of COVID-19

Rubina K Mahajan et al. J Anaesthesiol Clin Pharmacol. 2020 Oct-Dec.

Abstract

Coronavirus disease 2019 (COVID-19), caused due to a novel coronavirus SARS-CoV-2, has swept across the planet and has become a public health emergency of international concern. Like other coronaviruses, it predominantly involves the respiratory system. However, several atypical manifestations of the disease have been reported worldwide in a short span of time. Almost all organ systems (cardiovascular, gastrointestinal, renal, hepatic, endocrine, and nervous system) have been reported to be involved. This review concisely summarizes the systemic effects of COVID-19, thus emphasizing that the disease can present in various forms and the healthcare workers need to be extra vigilant, approaching all patients with a high index of suspicion.

Keywords: Coronavirus; SARS-CoV-2; manifestations; nineteen.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Systemic manifestations of COVID-19
See this image and copyright information in PMC

References

    1. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727–33. - PMC - PubMed
    1. Naming the coronavirus disease (COVID-19) and the virus that causes it [Internet] [[cited 2020 Apr 12]]. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technica... .
    1. Yu ITS, Li Y, Wong TW, Tam W, Chan AT, Lee JH, et al. Evidence of airborne transmission of the severe acute respiratory syndrome virus. N Engl J Med. 2004;350:1731–9. - PubMed
    1. Modes of transmission of virus causing COVID-19: Implications for IPC precaution recommendations [Internet] [[cited 2020 Apr 12]]. Available from: https://www.who.int/news-room/commentaries/detail/modes-of-transmission-... .
    1. Shereen MA, Khan S, Kazmi A, Bashir N, Siddique R. COVID-19 infection: Origin, transmission, and characteristics of human coronaviruses. J Adv Res. 2020;24:91–8. - PMC - PubMed