Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2021 Mar 26:12:662878.
doi: 10.3389/fphys.2021.662878. eCollection 2021.

New Challenges in Systems Biology: Understanding the Holobiont

Affiliations
Editorial

New Challenges in Systems Biology: Understanding the Holobiont

Maximino Aldana et al. Front Physiol. .
No abstract available

Keywords: challenge; complex ecosystem; dynamics; evolution; holobiont; systems biology.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

    1. Abbot A. (2016, January 08). Scientists bust myth that our bodies have more bacteria than human cells. Nature News. 10.1038/nature.2016.19136 - DOI
    1. Alegado R. A., Brown L. W., Cao S., Dermenjian R. K., Zuzow R., Fairclough S. R., et al. . (2012). A bacterial sulfonolipid triggers multicellular development in the closest living relatives of animals. eLife 1:e00013. 10.7554/eLife.00013.030 - DOI - PMC - PubMed
    1. Bates J. M., Mittge E., Kuhlman J., Baden K. N., Cheesman S. E., Guillemin K. (2006). Distinct signals from the microbiota promote different aspects of zebrafish gut differentiation. Dev. Biol. 297, 374–386. 10.1016/j.ydbio.2006.05.006 - DOI - PubMed
    1. Bordenstein S. R., Theis K. R. (2015). Host biology in light of the microbiome: ten principles of holobionts and hologenomes. PLoS Biol. 13:e1002226. 10.1371/journal.pbio.1002226 - DOI - PMC - PubMed
    1. Carpenter J. (2012). Multicellularity driven by bacteria. Science 337:510. 10.1126/science.337.6094.510 - DOI - PubMed

Publication types

LinkOut - more resources